An efficient production of bio-succinate in a novel metabolically engineered Klebsiella oxytoca by rational metabolic engineering and evolutionary adaptation
C Phosriran, N Wong, K Jantama - Bioresource Technology, 2024 - Elsevier
Abstract Klebsiella oxytoca KC004 (ΔadhEΔpta-ackAΔldhAΔbudABΔpflB) was engineered
to enhance succinate production. The strain exhibited poor growth without succinate …
to enhance succinate production. The strain exhibited poor growth without succinate …
Optimization of fermentation conditions as a metabolic strategy for the high-yield and high-selectivity bio-based 2, 3-butanediol production
Optimization of culture conditions can be used as an alternative metabolic control strategy to
genetic engineering to improve bio-based 2, 3-butanediol (2, 3-BDO) production, especially …
genetic engineering to improve bio-based 2, 3-butanediol (2, 3-BDO) production, especially …
Sustainable production of optically pure platform chemical bio-based (R, R)− 2, 3-butanediol from sugarcane molasses in a low-cost salt medium
Abstract Bio-based 2, 3-butanediol (2, 3-BDO) viability production on a large scale depends
on the culture medium costs, fermentation broth, and bioprocess biosafety. This study …
on the culture medium costs, fermentation broth, and bioprocess biosafety. This study …
Engineering Escherichia coli for a high yield of 1,3-propanediol near the theoretical maximum through chromosomal integration and gene deletion
N Wong, K Jantama - Applied Microbiology and Biotechnology, 2022 - Springer
Abstract Glycerol dehydratase (gdrAB-dhaB123) operon from Klebsiella pneumoniae and
NADPH-dependent 1, 3-propanediol oxidoreductase (yqhD) from Escherichia coli were …
NADPH-dependent 1, 3-propanediol oxidoreductase (yqhD) from Escherichia coli were …
Efficient L-valine production using systematically metabolic engineered Klebsiella oxytoca
M Cao, W Sun, S Wang, H Di, Q Du, X Tan… - Bioresource …, 2024 - Elsevier
L-Valine, a branched-chain amino acid with diversified applications, is biosynthesized with α-
acetolactate as the key precursor. In this study, the metabolic flux in Klebsiella oxytoca PDL …
acetolactate as the key precursor. In this study, the metabolic flux in Klebsiella oxytoca PDL …
Production of α-ketoisovalerate with whey powder by systemic metabolic engineering of Klebsiella oxytoca
W Sun, S Wang, X Tan, L Guo, W Liu, W Tian… - Microbial Cell …, 2024 - Springer
Background Whey, which has high biochemical oxygen demand and chemical oxygen
demand, is mass-produced as a major by-product of the dairying industry. Microbial …
demand, is mass-produced as a major by-product of the dairying industry. Microbial …
Relationship between feeding strategies and nitrogen sources in platform chemical bio-based 2, 3-butanediol production in fed-batch fermentation
D Tinôco, RPV de Castro, D Teixeira… - Reaction Chemistry & …, 2023 - pubs.rsc.org
Bio-based 2, 3-BDO production can be improved through fed-batch fermentation and
nutritional control. This study investigated the relationship between different feeding profiles …
nutritional control. This study investigated the relationship between different feeding profiles …
Sustainable bio-based 2, 3-butanediol production from renewable feedstocks
D Tinôco - Agricultural Biomass for the Synthesis of Value-Added …, 2024 - taylorfrancis.com
The energy transition from fossil resources to renewable resources-based industries has
stimulated the traditional bulk chemicals production by the biological route. 2, 3-Butanediol …
stimulated the traditional bulk chemicals production by the biological route. 2, 3-Butanediol …
Optimization of hydrolysis of cassava starch for biofuel production using a Hybrid Metaheuristic Algorithm
MAC Benvenga, IA Nääs - Biomass Conv. Bioref, 2022 - Springer
Biofuels are a current alternative to promote cleaner energy, minimizing environmental
impacts of transport worldwide. One of the sources of these biofuels is cassava starch, which …
impacts of transport worldwide. One of the sources of these biofuels is cassava starch, which …