Purpose MiR-155 is a member of the microRNAs (miRNAs) family and regulates gene
expression post-transcriptionally by binding to the 3'UTR of target mRNA. MiR-155 has a …

Multiple sclerosis (MS) is a leading cause of progressive disability among young adults
caused by inflammation, demyelination and axonal loss in the central nervous system. Small …

Human mesenchymal stem cell (hMSC) derived extracellular vesicles (EVs) have shown
therapeutic potential in recent studies. However, the corresponding therapeutic components …

Sex differences are present across multiple non-reproductive organ cancers, with male
individuals generally experiencing higher incidence of cancer with poorer outcomes …

Background/Aims: A reduced prevalence of circulating regulatory T cells (Tregs) is a
hallmark of inflammatory rheumatoid arthritis (RA). However, the underlying mechanisms of …

In the Russian Federation, multiple sclerosis prevalence rates vary from 10 to 80 cases per
100,000, depending on region and the nationality of the population. The main characteristics …

Exosomes are small extracellular vesicles with a complex lipid-bilayer surface and 30–150
nm diameter. These vesicles play a critical role in intercellular signaling networks during …

Exosomal microRNAs (miRNAs) are emerging diagnostic biomarkers for neurodegenerative
diseases. In this study, we aimed to detect relapsing–remitting multiple sclerosis (RRMS) …

Cognitive deficits strongly affect the quality of life of patients with multiple sclerosis (MS).
However, no cognitive MS biomarkers are currently available. Extracellular vesicles (EVs) …

Introduction: Multiple Sclerosis (MS) is the most common immune-mediated chronic
neurodegenerative disease of the central nervous system (CNS) affecting young people …