[HTML][HTML] Journey to the centre of the lung. The perspective of a mineralogist on the carcinogenic effects of mineral fibres in the lungs
AF Gualtieri - Journal of Hazardous Materials, 2023 - Elsevier
This work reviews the bio-chemical mechanisms leading to adverse effects produced when
mineral fibres are inhaled and transported in the lungs from the perspective of a …
mineral fibres are inhaled and transported in the lungs from the perspective of a …
History of dental biomaterials: Biocompatibility, durability and still open challenges
E Marin - Heritage Science, 2023 - Springer
Objective This review paper aims to provide a comprehensive understanding of the
historical evolution of dental biomaterials, as well as to understand the reasons behind their …
historical evolution of dental biomaterials, as well as to understand the reasons behind their …
[HTML][HTML] Variation in dissolution behavior among different nanoforms and its implication for grouping approaches in inhalation toxicity
Different nanoforms (NF) of the same substance each need to be registered under REACH,
but similarities in physiological interaction-among them biodissolution-can justify read …
but similarities in physiological interaction-among them biodissolution-can justify read …
[HTML][HTML] Bridging the gap between toxicity and carcinogenicity of mineral fibres by connecting the fibre crystal-chemical and physical parameters to the key …
AF Gualtieri - Current research in toxicology, 2021 - Elsevier
Airborne fibres and particularly asbestos represent hazards of great concern for human
health because exposure to these peculiar particulates may cause malignancies such as …
health because exposure to these peculiar particulates may cause malignancies such as …
Characterization and assessment of the potential toxicity/pathogenicity of Russian commercial chrysotile
Today, cancer is one of the main health issues faced in the workplace, with asbestos an
important carcinogen in the occupational environment. Among the asbestos minerals …
important carcinogen in the occupational environment. Among the asbestos minerals …
Understanding dissolution rates via continuous flow systems with physiologically relevant metal ion saturation in lysosome
Dissolution rates of nanomaterials can be decisive for acute in vivo toxicity (via the released
ions) and for biopersistence (of the remaining particles). Continuous flow systems (CFSs) …
ions) and for biopersistence (of the remaining particles). Continuous flow systems (CFSs) …
Could soluble minerals be hazardous to human health? Evidence from fibrous epsomite
From a toxicological point of view, particulates and fibres with high solubility in water and/or
in biological environments have not been considered in detail and the knowledge to date in …
in biological environments have not been considered in detail and the knowledge to date in …
Acute cytotoxicity of mineral fibres observed by time-lapse video microscopy
Inhalation of mineral fibres is associated with the onset of an inflammatory activity in the
lungs and the pleura responsible for the development of fatal malignancies. It is known that …
lungs and the pleura responsible for the development of fatal malignancies. It is known that …
[HTML][HTML] The acute toxicity of mineral Fibres: A systematic in vitro study using different THP-1 macrophage phenotypes
S Mirata, V Almonti, D Di Giuseppe, L Fornasini… - International journal of …, 2022 - mdpi.com
Alveolar macrophages are the first line of defence against detrimental inhaled stimuli. To
date, no comparative data have been obtained on the inflammatory response induced by …
date, no comparative data have been obtained on the inflammatory response induced by …
Occurrence, behaviour, and human exposure pathways and health risks of toxic geogenic contaminants in serpentinitic ultramafic geological environments (SUGEs) …
W Gwenzi - Science of The Total Environment, 2020 - Elsevier
Serpentinitic ultramafic geological environments (SUGEs) contain toxic geogenic
contaminants (TGCs). Yet comprehensive reviews on the medical geology of SUGEs are still …
contaminants (TGCs). Yet comprehensive reviews on the medical geology of SUGEs are still …