The international consensus classification of myeloid neoplasms and acute leukemias: myeloproliferative neoplasms
J Thiele, HM Kvasnicka, A Orazi… - American journal of …, 2023 - Wiley Online Library
A group of international experts, including hematopathologists, oncologists, and geneticists
were recently summoned (September 2021, Chicago, IL, USA) to update the 2016/17 World …
were recently summoned (September 2021, Chicago, IL, USA) to update the 2016/17 World …
Cardiovascular Disease in Myeloproliferative Neoplasms: JACC: CardioOncology State-of-the-Art Review
O Leiva, G Hobbs, K Ravid, P Libby - Cardio Oncology, 2022 - jacc.org
Myeloproliferative neoplasms are associated with increased risk for thrombotic
complications. These conditions most commonly involve somatic mutations in genes that …
complications. These conditions most commonly involve somatic mutations in genes that …
JAK2V617F mutation is highly prevalent in patients with ischemic stroke: a case-control study
MH Kristiansen, L Kjær, V Skov, MK Larsen… - Blood …, 2023 - ashpublications.org
Ischemic stroke has a high recurrence rate despite treatment. This underlines the
significance of investigating new possible cerebrovascular risk factors, such as the acquired …
significance of investigating new possible cerebrovascular risk factors, such as the acquired …
A randomized double-blind trial of 3 aspirin regimens to optimize antiplatelet therapy in essential thrombocythemia
Essential thrombocythemia (ET) is characterized by abnormal megakaryopoiesis and
enhanced thrombotic risk. Once-daily low-dose aspirin is the recommended antithrombotic …
enhanced thrombotic risk. Once-daily low-dose aspirin is the recommended antithrombotic …
Clinical insights into the origins of thrombosis in myeloproliferative neoplasms
AR Moliterno, YZ Ginzburg… - Blood, The Journal of the …, 2021 - ashpublications.org
Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs), polycythemia
vera, essential thrombocythemia, and primary myelofibrosis, are hematopoietic stem cell …
vera, essential thrombocythemia, and primary myelofibrosis, are hematopoietic stem cell …
International Consensus Classification of myeloid and lymphoid neoplasms: myeloproliferative neoplasms
U Gianelli, J Thiele, A Orazi, N Gangat, AM Vannucchi… - Virchows Archiv, 2023 - Springer
Abstract The recently published International Consensus Classification (ICC) of myeloid
neoplasms summarized the results of an in-depth effort by pathologists, oncologists, and …
neoplasms summarized the results of an in-depth effort by pathologists, oncologists, and …
Thrombotic, inflammatory, and HIF-regulated genes and thrombosis risk in polycythemia vera and essential thrombocythemia
Thrombosis is a major cause of morbidity and mortality in polycythemia vera (PV) and
essential thrombocythemia (ET). The pathophysiology of thrombosis in these disorders …
essential thrombocythemia (ET). The pathophysiology of thrombosis in these disorders …
Direct oral anticoagulants for myeloproliferative neoplasms: results from an international study on 442 patients
DOACs emerged as a treatment of choice for secondary prevention of VTE and thrombosis
prophylaxis in AF in the general population, and may be an attractive alternative to VKAs in …
prophylaxis in AF in the general population, and may be an attractive alternative to VKAs in …
Platelet Dysfunction and Thrombosis in JAK2V617F-Mutated Primary Myelofibrotic Mice
S Matsuura, CR Thompson… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: The risk of thrombosis in myeloproliferative neoplasms, such as primary
myelofibrosis varies depending on the type of key driving mutation (JAK2 [janus kinase 2] …
myelofibrosis varies depending on the type of key driving mutation (JAK2 [janus kinase 2] …
Platelets and neutrophils cooperate to induce increased neutrophil extracellular trap formation in JAK2V617F myeloproliferative neoplasms
A Guy, G Garcia, V Gourdou-Latyszenok… - Journal of Thrombosis …, 2024 - Elsevier
Background Neutrophils participate in the pathogenesis of thrombosis through the formation
of neutrophil extracellular traps (NETs). Thrombosis is the main cause of morbidity and …
of neutrophil extracellular traps (NETs). Thrombosis is the main cause of morbidity and …