The association between nutrition, obesity, inflammation, and endometrial cancer: a scoping review

TO Thrastardottir, VJ Copeland… - Current Nutrition …, 2023 - Springer
Abstract Purpose of Review Endometrial cancer is the most common gynecological
malignancy and represents a notorious threat to women's health worldwide. Endometrial …

New actors driving the epithelial–mesenchymal transition in cancer: the role of leptin

M Olea-Flores, JC Juárez-Cruz, MD Zuñiga-Eulogio… - Biomolecules, 2020 - mdpi.com
Leptin is a hormone secreted mainly by adipocytes; physiologically, it participates in the
control of appetite and energy expenditure. However, it has also been linked to tumor …

[HTML][HTML] Leptin stimulates migration and invasion and maintains cancer stem-like properties in ovarian cancer cells: an explanation for poor outcomes in obese women

S Kato, L Abarzua-Catalan, C Trigo, A Delpiano… - Oncotarget, 2015 - ncbi.nlm.nih.gov
The evidence linking obesity with ovarian cancer remains controversial. Leptin is expressed
at higher levels in obese women and stimulates cell migration in other epithelial cancers …

[PDF][PDF] Involvement of leptin receptors expression in proliferation and neoangiogenesis in colorectal carcinoma

VS Milosevic, FC Vukmirovic, MS Krstic, MM Zindovic… - J buon, 2015 - jbuon.com
Purpose: This study tested whether there exists a correlation between leptin receptors
(LEPR) expression with proliferation and neoangiogenesis in colorectal carcinoma …

[HTML][HTML] Gynaecological cancers and leptin: A focus on the endometrium and ovary

A Ray, J Fornsaglio, S Dogan, S Hedau… - Facts, Views & Vision …, 2018 - ncbi.nlm.nih.gov
Obesity has an influence on the risk and prognosis of different types of cancers of the female
reproductive tract. In the uterus, a common site for neoplasms is the endometrium, the inner …

[PDF][PDF] Clinical significance of Leptin receptor (LEPR) and Endoglin (CD105) expressions in colorectal adenocarcinoma

MS Vuletic, VS Milosevic, SA Jancic, JT Zujovic… - J buon, 2019 - jbuon.com
Purpose: Carcinoma of the colon occurs quite more often in obese than in healthy people.
The key molecule in the development of obesity is leptin, a product of Ob gene that …

[PDF][PDF] Interplay between expression of leptin receptors and mucin histochemical aberrations in colorectal adenocarcinoma

V Milosevic, F Vukmirovic, M Zindovic, M Krstic… - Rom. J. Morphol …, 2015 - rjme.ro
Background: There is no information on the effects of leptin receptors expression on mucin-
histochemical alterations in human colorectal adenocarcinoma. Aim: Testing the correlation …

[PDF][PDF] Leptin receptor expression during the progression of endometrial carcinoma is correlated with estrogen and progesterone receptors

LF Méndez-López, A Zavala-Pompa… - Archives of medical …, 2017 - termedia.pl
Results: We found that Ob-R expression was positively correlated with that of ER and PR (r=
1, p< 0.001; r= 0.943, p< 0.005, respectively), and there was a significant difference in Ob-R …

Linking obesity-induced leptin-signaling pathways to common endocrine-related cancers in women

E Nyasani, I Munir, M Perez, K Payne, S Khan - Endocrine, 2019 - Springer
Obesity is related to many major diseases and cancers. Women have higher rates of obesity
and obesity is linked to commonly occurring cancers in women. However, there is a lack of …

The Effect of Serum Leptin Concentration and Leptin Receptor Expression on Colorectal Cancer

S Chludzińska-Kasperuk, J Lewko… - International Journal of …, 2023 - mdpi.com
Introduction: The level of leptin in the blood shows a positive, strong correlation with the
mass of adipose tissue. Being overweight and having metabolic disorders increase the risk …