Abstract Resveratrol, trans 3, 5, 4′-trihydroxystilbene, is a stilbenoid polyphenol with a wide
range of properties including antioxidant, neuroprotective, cardioprotective, anti …

The nuclear long non-coding RNA LUCAT1 has previously been identified as a negative
feedback regulator of type I interferon and inflammatory cytokine expression in human …

Glioblastoma (GBM) constitutes the most lethal primary brain tumor for which
immunotherapy has provided limited benefit. The unique brain immune landscape is …

Although beta-endorphinergic neurons in the hypothalamic arcuate nucleus (ARC)
synthesize beta-endorphin (β-EP) to alleviate nociceptive behaviors, the underlying …

Background Neuroinflammation and blood-brain barrier (BBB) disruption are two vital
mechanisms of secondary brain injury following intracerebral hemorrhage (ICH). Recently …

The NR4A family of orphan nuclear receptors (Nr4a1–3) plays redundant roles to establish
and maintain Treg identity; deletion of multiple family members in the thymus results in Treg …

Background Macrophages play a pivotal role in atherosclerotic plaque development. Recent
evidence has suggested the glucagon-like peptide-1 receptor (GLP-1R) agonist, liraglutide …

Background Exposure to heat stress suppresses poultry immune responses, which can
increase susceptibility to infectious diseases and, thereby, intensify the negative effects of …

Adenosine (Ado) is significantly elevated in the tumor microenvironment (TME) compared to
normal tissues. It binds to adenosine receptors (AdoRs), suppressing tumor antigen …

Pristane causes chronic peritoneal inflammation resulting in lupus, which in C57BL/6 mice is
complicated by lung microvascular injury and diffuse alveolar hemorrhage (DAH). Mineral …