Glutathione is the principal intracellular antioxidant buffer against oxidative stress and
mainly exists in the forms of reduced glutathione (GSH) and oxidized glutathione (GSSG) …

The physiological roles played by the tripeptide glutathione have greatly advanced over the
past decades superimposing the research on free radicals, oxidative stress and, more …

BACKGROUND: Glutathione (GSH) is present in all mammalian tissues as the most
abundant non-protein thiol that defends against oxidative stress. GSH is also a key …

Cerium oxide nanoparticles (nanoceria) have shown promise as catalytic antioxidants in the
test tube, cell culture models and animal models of disease. However given the reactivity …

Nanotechnology promises a revolution in pharmacology to improve or create ex novo
therapies. Cerium oxide nanoparticles (nanoceria), well-known as catalysts, possess an …

Reactive oxygen species (ROS) produced by cellular metabolism play an important role as
signaling messengers in immune system. ROS elevated in the tumor microenvironment are …

Glutathione (GSH) is a ubiquitous intracellular peptide with diverse functions that include
detoxification, antioxidant defense, maintenance of thiol status, and modulation of cell …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play important roles in
regulation of cell survival. In general, moderate levels of ROS/RNS may function as signals …

Glutathione (GSH) plays an important role in a multitude of cellular processes, including cell
differentiation, proliferation, and apoptosis, and as a result, disturbances in GSH …

Abstract gadd153, also known as chop, is a highly stress-inducible gene that is robustly
expressed following disruption of homeostasis in the endoplasmic reticulum (ER)(so-called …