Immuno‐oncology (IO) is a fast‐expanding field due to recent success using IO therapies in
treating cancer. As IO therapies do not directly kill tumor cells but rather act upon the …

A mathematical model describing the growth of tumor cells and the effect of impulsive
therapy is studied in this paper. The governing equations and parameters related to the …

Simple Summary CAR-T cell immunotherapy uses engineered T lymphocytes to recognize
cancer antigens and to directly attack cancer cells and have been successfully used against …

A mathematical model is proposed to study the complicated dynamics of tumor-immune
interactions with three discrete time delays. The proposed model consists of nine coupled …

In this paper, we review some recent results on the nonlinear dynamics of delayed
differential equation models describing the interaction between tumor cells and effector cells …

Immunotherapy, by enhancing the endogenous anti-tumor immune responses, is showing
promising results for the treatment of numerous cancers refractory to conventional therapies …

Accurate and reliable model representations of cancer dynamics are milestones in the field
of cancer research. Mathematical modeling approaches are abundantly used in cancer …

Abstract Background and Objective There are various approaches to control a mathematical
dynamic of cancer, each of which is suitable for a special goal. Optimal control is considered …

This work presents a new mathematical model to depict the effect of obesity on cancerous
tumor growth when chemotherapy and immunotherapy have been administered. We …

This study is designed to present an agent-based model (ABM) to simulate the interactions
between tumor cells and the immune system in the melanoma model. The Myeloid-derived …