Unraveling the allosteric communication mechanisms in T-cell receptor–peptide-loaded major histocompatibility complex dynamics using molecular dynamics …
Antigen presentation by major histocompatibility complex (MHC) proteins to T-cell receptors
(TCRs) plays a crucial role in triggering the adaptive immune response. Most of our …
(TCRs) plays a crucial role in triggering the adaptive immune response. Most of our …
Non-Apoptotic caspase activity preferentially targets a novel consensus sequence associated with cytoskeletal proteins in the developing auditory brainstem
F Weghorst, Y Mirzakhanyan, KL Hernandez… - Frontiers in Cell and …, 2022 - frontiersin.org
The auditory brainstem relies on precise circuitry to facilitate sound source localization. In
the chick, the development of this specialized circuitry requires non-apoptotic activity of …
the chick, the development of this specialized circuitry requires non-apoptotic activity of …
Revealing the Dynamic Changes Induced by Various Peptides on TCR-pMHC via Molecular Dynamics Simulation Techniques
ENB Aksoy - 2024 - search.proquest.com
Allostery, a crucial phenomenon for comprehending protein function, interactions, and
regulation, involves the transmission of perturbations induced by ligand binding to distant …
regulation, involves the transmission of perturbations induced by ligand binding to distant …
Water-mediated structural rearrangement establishes active conformation of caspases for apoptosis and inflammation
A Sharma, P Gogoi, M Chandravanshi… - Journal of …, 2022 - Taylor & Francis
Caspases are c ysteine-dependent asp artate-specific prote ases that play a crucial role in
apoptosis (or programmed cell death) and inflammation. Based on their function, caspases …
apoptosis (or programmed cell death) and inflammation. Based on their function, caspases …
[图书][B] Mechanisms of non-apoptotic roles for apoptotic proteins in development of the chick auditory brainstem
F Weghorst - 2022 - search.proquest.com
The auditory brainstem is specialized to localize sounds with extreme temporal precision,
which requires highly accurate development of the circuit that facilitates this function. In the …
which requires highly accurate development of the circuit that facilitates this function. In the …