Fungi that infect humans

JR Köhler, B Hube, R Puccia, A Casadevall… - Microbiology …, 2017 - Am Soc Microbiol
Fungi must meet four criteria to infect humans: growth at human body temperatures,
circumvention or penetration of surface barriers, lysis and absorption of tissue, and …

Metals in fungal virulence

F Gerwien, V Skrahina, L Kasper… - FEMS microbiology …, 2018 - academic.oup.com
Metals are essential for life, and they play a central role in the struggle between infecting
microbes and their hosts. In fact, an important aspect of microbial pathogenesis is the …

[HTML][HTML] Is copper beneficial for COVID-19 patients?

S Raha, R Mallick, S Basak, AK Duttaroy - Medical hypotheses, 2020 - Elsevier
Copper (Cu) is an essential micronutrient for both pathogens and the hosts during viral
infection. Cu is involved in the functions of critical immune cells such as T helper cells, B …

[HTML][HTML] Associations of essential and toxic metals/metalloids in whole blood with both disease severity and mortality in patients with COVID‐19

HL Zeng, Q Yang, P Yuan, X Wang, L Cheng - The FASEB Journal, 2021 - ncbi.nlm.nih.gov
The variations and dynamics of essential and toxic metal (loid) s in patients with COVID‐19
may associate with the progression and fatal outcome of the disease, which still remains to …

The first isolate of Candida auris in China: clinical and biological aspects

X Wang, J Bing, Q Zheng, F Zhang, J Liu… - Emerging microbes & …, 2018 - Taylor & Francis
The emerging human fungal pathogen Candida auris has been recognized as a multidrug
resistant species and is associated with high mortality. This fungus was first described in …

[HTML][HTML] Cell biology of Candida albicans–host interactions

A da Silva Dantas, KK Lee, I Raziunaite… - Current opinion in …, 2016 - Elsevier
Highlights•The cell biology of Candida albicans is adapted both for life as a commensal and
as a pathogen.•C. albicans can either downregulate or upregulate virulence properties in …

The Yin and Yang of copper during infection

AN Besold, EM Culbertson, VC Culotta - JBIC Journal of Biological …, 2016 - Springer
Copper is an essential micronutrient for both pathogens and the animal hosts they infect.
However, copper can also be toxic in cells due to its redox properties and ability to disrupt …

Potential molecular mechanisms of zinc-and copper-mediated antiviral activity on COVID-19

I Rani, A Goyal, M Bhatnagar, S Manhas, P Goel, A Pal… - Nutrition Research, 2021 - Elsevier
Abstract Novel coronavirus disease 2019 (COVID-19) has spread across the globe; and
surprisingly, no potentially protective or therapeutic antiviral molecules are available to treat …

Copper signaling in the brain and beyond

CM Ackerman, CJ Chang - Journal of Biological Chemistry, 2018 - ASBMB
Transition metals have been recognized and studied primarily in the context of their
essential roles as structural and metabolic cofactors for biomolecules that compose living …

Emergence and evolution of virulence in human pathogenic fungi

S Siscar-Lewin, B Hube, S Brunke - Trends in microbiology, 2022 - cell.com
One billion people worldwide are affected by fungal pathogens, of which 1.6 million
succumb to fungal infections per year. This review discusses the emergence and evolution …