High-fat, western-style diet, systemic inflammation, and gut microbiota: a narrative review
IJ Malesza, M Malesza, J Walkowiak, N Mussin… - Cells, 2021 - mdpi.com
The gut microbiota is responsible for recovering energy from food, providing hosts with
vitamins, and providing a barrier function against exogenous pathogens. In addition, it is …
vitamins, and providing a barrier function against exogenous pathogens. In addition, it is …
Interaction between lipopolysaccharide and gut microbiota in inflammatory bowel diseases
Lipopolysaccharides (LPSs) are bacterial surface glycolipids, produced by Gram-negative
bacteria. LPS is known to determine acute inflammatory reactions, particularly in the context …
bacteria. LPS is known to determine acute inflammatory reactions, particularly in the context …
Western diets and chronic diseases
TE Adolph, H Tilg - Nature medicine, 2024 - nature.com
Abstract 'Westernization', which incorporates industrial, cultural and dietary trends, has
paralleled the rise of noncommunicable diseases across the globe. Today, the Western-style …
paralleled the rise of noncommunicable diseases across the globe. Today, the Western-style …
[HTML][HTML] Obesity and the western diet: How we got here
V Rakhra, SL Galappaththy, S Bulchandani… - Missouri …, 2020 - ncbi.nlm.nih.gov
Through the course of the last several decades, the rate of obesity has progressively
increased and is now one of the leading causes of death worldwide. The World Health …
increased and is now one of the leading causes of death worldwide. The World Health …
Very‐low‐carbohydrate diet enhances human T‐cell immunity through immunometabolic reprogramming
S Hirschberger, G Strauß, D Effinger… - EMBO Molecular …, 2021 - embopress.org
Very‐low‐carbohydrate diet triggers the endogenous production of ketone bodies as
alternative energy substrates. There are as yet unproven assumptions that ketone bodies …
alternative energy substrates. There are as yet unproven assumptions that ketone bodies …
Enriched dietary saturated fatty acids induce trained immunity via ceramide production that enhances severity of endotoxemia and clearance of infection
AL Seufert, JW Hickman, SK Traxler, RM Peterson… - Elife, 2022 - elifesciences.org
Trained immunity is an innate immune memory response that is induced by a primary
inflammatory stimulus that sensitizes monocytes and macrophages to a secondary …
inflammatory stimulus that sensitizes monocytes and macrophages to a secondary …
Western diet induces impairment of liver-brain axis accelerating neuroinflammation and amyloid pathology in Alzheimer's Disease
A Wiȩckowska-Gacek… - Frontiers in aging …, 2021 - frontiersin.org
Alzheimer's disease (AD) is an aging-dependent, irreversible neurodegenerative disorder
and the most common cause of dementia. The prevailing AD hypothesis points to the central …
and the most common cause of dementia. The prevailing AD hypothesis points to the central …
Urban living in healthy Tanzanians is associated with an inflammatory status driven by dietary and metabolic changes
Abstract Sub-Saharan Africa currently experiences an unprecedented wave of urbanization,
which has important consequences for health and disease patterns. This study aimed to …
which has important consequences for health and disease patterns. This study aimed to …
Targeting gut barrier dysfunction with phytotherapies: Effective strategy against chronic diseases
P Dey - Pharmacological research, 2020 - Elsevier
The intestinal epithelial layer serves as a physical and functional barrier between the
microbe-rich lumen and immunologically active submucosa; it prevents systemic …
microbe-rich lumen and immunologically active submucosa; it prevents systemic …
[HTML][HTML] New insights into lipopolysaccharide inactivation mechanisms in sepsis
EG Pérez-Hernández, B Delgado-Coello… - Biomedicine & …, 2021 - Elsevier
The complex pathophysiology of sepsis makes it a syndrome with limited therapeutic options
and a high mortality rate. Gram-negative bacteria containing lipopolysaccharides (LPS) in …
and a high mortality rate. Gram-negative bacteria containing lipopolysaccharides (LPS) in …