COVID-19 and olfactory dysfunction: a looming wave of dementia?

LM Kay - Journal of neurophysiology, 2022 - journals.physiology.org
Olfactory dysfunction is a hallmark symptom of COVID-19 disease resulting from the SARS-
CoV-2 virus. The cause of the sudden and usually temporary anosmia that most people …

Olfactory identification testing as a predictor of the development of Alzheimer's dementia: a systematic review

GH Sun, CA Raji, MP MacEachern… - The …, 2012 - Wiley Online Library
Abstract Objectives/Hypothesis: To evaluate the utility of olfactory identification tests as
prognostic instruments for Alzheimer's dementia (AD). Study Design: Systematic review …

Discriminant analysis of longitudinal cortical thickness changes in Alzheimer's disease using dynamic and network features

Y Li, Y Wang, G Wu, F Shi, L Zhou, W Lin, D Shen… - Neurobiology of …, 2012 - Elsevier
Neuroimage measures from magnetic resonance (MR) imaging, such as cortical thickness,
have been playing an increasingly important role in searching for biomarkers of Alzheimer's …

Assessment of odor hedonic perception: the Sniffin'sticks parosmia test (SSParoT)

DT Liu, A Welge-Lüssen, G Besser, CA Mueller… - Scientific reports, 2020 - nature.com
Qualitative olfactory dysfunction is characterized as distorted odor perception and can have
a profound effect on quality of life of affected individuals. Parosmia and phantosmia …

Olfaction and risk of dementia in a biracial cohort of older adults

K Yaffe, D Freimer, H Chen, K Asao, A Rosso, S Rubin… - Neurology, 2017 - AAN Enterprises
Objective: Prior studies indicate that olfactory function may be an early marker for cognitive
impairment, but the body of evidence has been largely restricted to white populations …

Olfactory assays for mouse models of neurodegenerative disease

AM Lehmkuhl, ER Dirr… - Journal of visualized …, 2014 - pmc.ncbi.nlm.nih.gov
In many neurodegenerative diseases and particularly in Parkinson's disease, deficits in
olfaction are reported to occur early in the disease process and may be a useful behavioral …

Evidence for early cognitive impairment related to frontal cortex in the 5XFAD mouse model of Alzheimer's disease

SD Girard, K Baranger, C Gauthier… - Journal of …, 2013 - content.iospress.com
The frontal cortex is a brain structure that plays an important role in cognition and is known
to be affected in Alzheimer's disease (AD) in humans. Over the past years, transgenic mouse …

Neuroimaging biomarkers and impaired olfaction in cognitively normal individuals

M Vassilaki, TJ Christianson, MM Mielke… - Annals of …, 2017 - Wiley Online Library
Objective There is a need for inexpensive noninvasive tests to identify older healthy persons
at risk for Alzheimer disease (AD) for enrollment in AD prevention trials. Our objective was to …

Amyloid-β deposition and olfactory dysfunction in an Alzheimer's disease model

N Wu, X Rao, Y Gao, J Wang… - Journal of Alzheimer's …, 2013 - content.iospress.com
Olfactory dysfunction is closely related to Alzheimer's disease (AD). Yet the mechanism
behind this dysfunction remains largely unknown. To clarify the relationship between …

Environmental toxicants-induced immune responses in the olfactory mucosa

F Imamura, S Hasegawa-Ishii - Frontiers in immunology, 2016 - frontiersin.org
Olfactory sensory neurons (OSNs) are the receptor cells for the sense of smell. Although cell
bodies are located in the olfactory mucosa (OM) of the nasal cavity, OSN axons directly …