Targeting drugs to tumours using cell membrane-coated nanoparticles
Traditional cancer therapeutics, such as chemotherapies, are often limited by their non-
specific nature, causing harm to non-malignant tissues. Over the past several decades …
specific nature, causing harm to non-malignant tissues. Over the past several decades …
CD4+ T cells in cancer
Cancer immunology and immunotherapy are driving forces of research and development in
oncology, mostly focusing on CD8+ T cells and the tumor microenvironment. Recent …
oncology, mostly focusing on CD8+ T cells and the tumor microenvironment. Recent …
Therapeutic cancer vaccines
M Saxena, SH van der Burg, CJM Melief… - Nature Reviews …, 2021 - nature.com
Therapeutic cancer vaccines have undergone a resurgence in the past decade. A better
understanding of the breadth of tumour-associated antigens, the native immune response …
understanding of the breadth of tumour-associated antigens, the native immune response …
[HTML][HTML] Turning cold tumors into hot tumors by improving T-cell infiltration
YT Liu, ZJ Sun - Theranostics, 2021 - ncbi.nlm.nih.gov
Immunotherapy, represented by immune checkpoint inhibitors (ICIs), has greatly improved
the clinical efficacy of malignant tumor therapy. ICI-mediated antitumor responses depend …
the clinical efficacy of malignant tumor therapy. ICI-mediated antitumor responses depend …
Bacterial cytoplasmic membranes synergistically enhance the antitumor activity of autologous cancer vaccines
Cancer vaccines based on resected tumors from patients have gained great interest as an
individualized cancer treatment strategy. However, eliciting a robust therapeutic effect with …
individualized cancer treatment strategy. However, eliciting a robust therapeutic effect with …
CD4+ T cell help in cancer immunology and immunotherapy
Cancer immunotherapy aims to promote the activity of cytotoxic T lymphocytes (CTLs) within
a tumour, assist the priming of tumour-specific CTLs in lymphoid organs and establish …
a tumour, assist the priming of tumour-specific CTLs in lymphoid organs and establish …
[HTML][HTML] Turning the corner on therapeutic cancer vaccines
RE Hollingsworth, K Jansen - npj Vaccines, 2019 - nature.com
Recent advances in several areas are rekindling interest and enabling progress in the
development of therapeutic cancer vaccines. These advances have been made in target …
development of therapeutic cancer vaccines. These advances have been made in target …
Engineered cell‐membrane‐coated nanoparticles directly present tumor antigens to promote anticancer immunity
The recent success of immunotherapies has highlighted the power of leveraging the
immune system in the fight against cancer. In order for most immune‐based therapies to …
immune system in the fight against cancer. In order for most immune‐based therapies to …
Recent advances in overcoming barriers to cell‐based delivery systems for cancer immunotherapy
Y Ding, Y Wang, Q Hu - Exploration, 2022 - Wiley Online Library
Immunotherapy strategies that use cell‐based delivery systems have sparked much interest
in the treatment of malignancies, owing to their high biocompatibility, excellent tumor …
in the treatment of malignancies, owing to their high biocompatibility, excellent tumor …
[HTML][HTML] Nanocarriers based on bacterial membrane materials for cancer vaccine delivery
Here we present a protocol for the construction and use of two types of nanocarrier based on
bacterial membrane materials for cancer vaccine delivery. Cancer vaccines induce tumor …
bacterial membrane materials for cancer vaccine delivery. Cancer vaccines induce tumor …