Viruses are intracellular parasites that use the host cell they infect to produce new infectious
progeny. Distinct steps of the virus life cycle occur in association with the cytoskeleton or …

In this review, we summarize the current knowledge about the membranous replication
factories of members of plus-strand (+) RNA viruses. We discuss primarily the architecture of …

Double-stranded RNA (dsRNA) longer than 30 bp is a key activator of the innate immune
response against viral infections. It is widely assumed that the generation of dsRNA during …

The cytoplasmic replication of positive-sense RNA viruses is associated with a dramatic
rearrangement of host cellular membranes. These virus-induced changes result in the …

Plus-strand RNA virus replication occurs in tight association with cytoplasmic host cell
membranes. Both, viral and cellular factors cooperatively generate distinct organelle-like …

Genome replication and assembly of viruses often takes place in specific intracellular
compartments where viral components concentrate, thereby increasing the efficiency of the …

The subcellular location of the nonstructural proteins NS1, NS2B, and NS3 in Vero cells
infected with the flavivirus Kunjin was investigated using indirect immunofluorescence and …

In a previous study on the replication of Kunjin virus using immunoelectron microscopy (EG
Westaway, JM Mackenzie, MT Kenney, MK Jones, and AA Khromykh, 1997, J. Virol. 71 …

During dengue virus infection of host cells, intracellular membranes are rearranged into
distinct subcellular structures such as double-membrane vesicles, convoluted membranes …

All plus-strand RNA viruses replicate in association with cytoplasmic membranes of infected
cells. The RNA replication complex of many virus families is associated with the …