Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage

R Muniyappa, S Lee, H Chen… - American Journal of …, 2008 - journals.physiology.org
Insulin resistance contributes to the pathophysiology of diabetes and is a hallmark of
obesity, metabolic syndrome, and many cardiovascular diseases. Therefore, quantifying …

Diabetes: models, signals, and control

C Cobelli, C Dalla Man, G Sparacino… - IEEE reviews in …, 2009 - ieeexplore.ieee.org
The control of diabetes is an interdisciplinary endeavor, which includes a significant
biomedical engineering component, with traditions of success beginning in the early 1960s …

Meal simulation model of the glucose-insulin system

C Dalla Man, RA Rizza, C Cobelli - IEEE Transactions on …, 2007 - ieeexplore.ieee.org
A simulation model of the glucose-insulin system in the postprandial state can be useful in
several circumstances, including testing of glucose sensors, insulin infusion algorithms and …

[图书][B] Handbook of membrane separations: chemical, pharmaceutical, food, and biotechnological applications

AK Pabby, SSH Rizvi, AMS Requena - 2008 - taylorfrancis.com
The Handbook of Membrane Separations: Chemical, Pharmaceutical, and Biotechnological
Applications provides detailed information on membrane separation technologies as they …

How to measure insulin sensitivity

E Ferrannini, A Mari - Journal of hypertension, 1998 - journals.lww.com
Insulin resistance is common in the general population and tends to cluster with glucose
intolerance, dyslipidaemia and high blood pressure. The importance of the insulin-resistant …

Partitioning glucose distribution/transport, disposal, and endogenous production during IVGTT

R Hovorka, F Shojaee-Moradie… - American Journal …, 2002 - journals.physiology.org
We have separated the effect of insulin on glucose distribution/transport, glucose disposal,
and endogenous production (EGP) during an intravenous glucose tolerance test (IVGTT) by …

Closed-loop insulin delivery—the path to physiological glucose control

GM Steil, AE Panteleon, K Rebrin - Advanced drug delivery reviews, 2004 - Elsevier
The development of an artificial pancreas for the treatment of insulin-dependent diabetes is
a highly desired endeavor for patients, physicians, scientists, and engineers. Historical …

Model Predictive Control of Type 1 Diabetes: An in Silico Trial

L Magni, DM Raimondo, L Bossi, C Dalla Man… - 2007 - journals.sagepub.com
Background: The development of artificial pancreas has received a new impulse from recent
technological advancements in subcutaneous continuous glucose monitoring and …

Insulin sensitivity and its measurement: structural commonalities among the methods

J Radziuk - The Journal of Clinical Endocrinology & Metabolism, 2000 - academic.oup.com
Insulin is the principal hormone of metabolic regulation. Reduced responses to insulin
constitute an underlying feature of type 2 diabetes. It is, therefore, incumbent on those who …

Age and diet modulate the insulin-sensitizing effects of exercise: a tracer-based oral glucose tolerance test

MA Vieira-Lara, AC Reijne, S Koshian, J Ciapaite… - Diabetes, 2023 - Am Diabetes Assoc
Diet modulates the development of insulin resistance during aging. This includes tissue-
specific alterations in insulin signaling and mitochondrial function, which ultimately affect …