The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …

Two decades ago successful transfection of antigen presenting cells (APC) in vivo was
demonstrated which resulted in the induction of primary adaptive immune responses. Due to …

Liposomes are a unique platform for drug delivery, and a number of liposomal formulations
have already been commercialized. Doxil is a representative example, which uses …

The complexity of nanoscale interactions between biomaterials and cells has limited the
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …

Nanovesicles and bio-vesicles (BVs) have emerged as promising tools to achieve targeted
cancer therapy due to their ability to overcome many of the key challenges currently being …

A key aspect for successful drug delivery via lipid‐based nanoparticles is their
internalization in target cells. Two prominent examples of such drug delivery systems are …

Biological drugs are attracting tremendous attention in disease treatment. However, their
application is significantly limited by their inherent properties, such as high hydrophilicity …

The delivery of nucleic acids with transient activity for genetic engineering is a promising
methodology with potential applications in the treatment of diseases ranging from cancer …

Nanocarriers have therapeutic potential to facilitate drug delivery, including biological
agents, small-molecule drugs, and nucleic acids. However, their efficiency is limited by …

As nanocarriers (NCs) can improve the solubility of drugs, prevent their degradation by
gastrointestinal (GI) enzymes and promote their transport across the mucus gel layer and …