Copper (Cu) is an essential micronutrient for most organisms and serves mainly as a redox-
active catalytic centre in enzymes cycling between Cu+ and Cu 2+. Membrane transporters …

Copper, which can potentially be a highly toxic agent, is an essential nutrient due to its role
as a cofactor for cuproenzymes and its participation in signaling pathways. In mammals, the …

Strong interest in copper homeostasis is due to the fact that copper is simultaneously a
catalytic co-factor of the vital enzymes, a participant in signaling, and a toxic agent provoking …

In the last 15 years, among the many reasons given for the development of idiopathic forms
of Parkinson's disease (PD), copper imbalance has been identified as a factor, and PD is …

Copper transport and accumulation were studied in virgin and lactating C57BL/6 mice, with
and without expression of ceruloplasmin (Cp), to assess the importance of Cp to these …

Медь необходима всем организмам, так как входит в состав активных центров
жизненно важных ферментов и участвует в сигналинге; в то же время свободные ионы …

Ceruloplasmin (Cp) is a multicopper ferroxidase that is considered to be an important source
of copper in milk for normal neonatal development. We investigated the expression …

Copper metabolism disturbances in mammary gland (MG) cells have severe consequences
in newborns. The mechanism that controls the balance of copper in the MG has not been …

Background Hyperglycemia‐related oxidative stress and hypoxia are important mechanisms
responsible for diabetes‐induced embryopathy and other complications. High sucrose low …

Tissue-specific regulation of the expression of ceruloplasmin (Cp) gene, which encodes
major copper-containing extracellular glycoprotein was investigated. A decrease of the Cp …