Background Multimorbidity, the co-occurrence of two or more chronic conditions, is common
among older adults and is known to be associated with high costs and gaps in quality of …

Rationale: Current evidence on the relationship between long-term exposure to air pollution
and new onset of chronic lung disease is inconclusive. Objectives: To examine associations …

Background Multimorbidity is common and associated with poor clinical outcomes and high
health care costs. Administrative data are a promising tool for studying the epidemiology of …

Background: People with a recent history of homelessness are believed to be at high risk of
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and, when …

Background: Few longitudinal studies have delineated the association between traditional
cardiovascular risk factors and development of aortic stenosis (AS). Objectives: The authors …

Importance Single-center studies identify frailty as a risk factor for 30-day postoperative
mortality. The long-term and population-level effect of frailty on postoperative mortality is, to …

Background: Population-based surveillance of Alzheimer's and related dementias (AD-RD)
incidence and prevalence is important for chronic disease management and health system …

Importance Controversy exists about the preferred surgical approach for total hip
arthroplasty (THA). Objective To determine whether an anterior approach is associated with …

Background Although chronic obstructive pulmonary disease (COPD) is one of the most
deadly, prevalent, and costly chronic diseases, no comprehensive estimates of the risk of …

Rationale There is growing evidence that air pollution may contribute to the development of
childhood asthma and other allergic diseases. In this follow-up of the Toronto Child Health …