Background Mental health conditions pose a major challenge to health care providers and
society at large. The World Health Organization predicts that by 2030, mental health …

Dysfunction of the mesocorticolimbic dopaminergic reward system is a core feature of
schizophrenia (SZ), yet its precise contributions to different stages of reward processing and …

It is increasingly recognized that multiple psychiatric conditions are underpinned by shared
neural pathways, affecting similar brain systems. Here, we carried out a multiscale neural …

Aberrations in how people form expectations about rewards and how they respond to
receiving rewards are thought to underlie major depressive disorder (MDD). However, the …

Individuals with autism experience substantially higher rates of mood problems compared to
the general population, which contribute to reduced quality of life and increased mortality …

Importance Schizophrenia spectrum disorders (SSDs) and autism spectrum disorder (ASD)
both feature social cognitive deficits; however, these disorders historically have been …

Anhedonia is a hallmark feature of depression and is highly prevalent among individuals
with mood disorders. The history and neurobiology of anhedonia has been most extensively …

Psychiatric disorders show high co-morbidity, including co-morbid expressions of subclinical
psychopathology across multiple disease spectra. Given the limitations of classical case …

Background This international study aimed to characterise the impact of acute SARS-CoV-2
infection in people with cystic fibrosis and investigate factors associated with severe …

Social prediction is a key feature of social cognition (SC), a function in which the modulating
role of the cerebellum is recognized. Accordingly, cerebellar alterations are reported in …