How any complex trait has evolved is a fascinating question, yet the evolution of parasitism
among the nematodes is arguably one of the most arresting. How did free-living nematodes …

Background Plant–parasitic nematode interactions occur within a vast molecular plant
immunity network. Following initial contact with the host plant roots, plant-parasitic …

Transgenesis for Strongyloides and Parastrongyloides was accomplished in 2006 and is
based on techniques derived for Caenorhabditis elegans over two decades earlier …

The infectious form of many parasitic nematodes, which afflict over one billion people
globally, is a developmentally arrested third-stage larva (L3i). The parasitic nematode …

Background With the paucity of new drugs and HIV co-infection, vaccination remains an
unmet research priority to combat visceral leishmaniasis (VL) requiring strong cellular …

Critical investigations into the cellular and molecular biology of parasitic nematodes have
been hindered by a lack of modern molecular genetic techniques for these organisms. One …

Infective third-stage larvae (L3i) of the human parasite Strongyloides stercoralis share many
morphological, developmental, and behavioral attributes with Caenorhabditis elegans dauer …

Based on metabolic and morphological similarities between infective third-stage larvae of
parasitic nematodes and dauer larvae of Caenorhabditis elegans, it is hypothesized that …

Background Iatrogenic infection of humans with Trichuris suis (a parasitic nematode of
swine) is being evaluated or promoted as a biological, curative treatment of immune …

The advent and integration of high-throughput'omic technologies (eg, genomics,
transcriptomics, proteomics and metabolomics) are becoming instrumental to assist …