Recent trends in preparation, investigation and application of polysaccharide-based chiral stationary phases for separation of enantiomers in high-performance liquid …

B Chankvetadze - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
This review article summarizes the recent developments in preparation, investigation and
application of polysaccharide-based chiral stationary phases for the separation of …

Recent advances in chromatography for pharmaceutical analysis

V D'Atri, S Fekete, A Clarke, JL Veuthey… - Analytical …, 2018 - ACS Publications
The pharmaceutical industry is one of the most regulated industries worldwide, since the
drug products have to be safe and effective. The levels of impurities and degradation …

Optical analysis of reaction yield and enantiomeric excess: a new paradigm ready for prime time

BT Herrera, SL Pilicer, EV Anslyn… - Journal of the …, 2018 - ACS Publications
This Perspective highlights the advances of optical methods for asymmetric reaction
discovery. Optical analysis allows for the determination of absolute configuration …

[HTML][HTML] Recent developments in the high-throughput separation of biologically active chiral compounds via high performance liquid chromatography

C De Luca, S Felletti, FA Franchina, D Bozza… - … of Pharmaceutical and …, 2024 - Elsevier
Bioactive compounds, including active pharmaceutical ingredients (APIs), are often chiral
molecules where stereoisomers have different biological and therapeutic activity …

Potency testing of cannabinoids by liquid and supercritical fluid chromatography: Where we are, what we need

S Felletti, C De Luca, A Buratti, D Bozza… - … of Chromatography A, 2021 - Elsevier
Hemp and cannabis industry is undergoing a renewed interest due to legalization of
marijuana (a topic that all countries are discussing, especially in recent years) and the …

Understanding the transition from high-selective to high-efficient chiral separations by changing the organic modifier with zwitterionic-teicoplanin chiral stationary …

S Felletti, C De Luca, G Mazzoccanti… - Analytical …, 2023 - ACS Publications
The retention behavior of small molecules and N-protected amino acids on a zwitterionic
teicoplanin chiral stationary phase (CSP), prepared on superficially porous particles (SPPs) …

Enantioselective liquid chromatographic separations using macrocyclic glycopeptide-based chiral selectors

R Berkecz, D Tanács, A Péter, I Ilisz - Molecules, 2021 - mdpi.com
Numerous chemical compounds of high practical importance, such as drugs, fertilizers, and
food additives are being commercialized as racemic mixtures, although in most cases only …

Analysis of enantiomers in products of food interest

C Fanali, G D'Orazio, A Gentili, S Fanali - Molecules, 2019 - mdpi.com
The separation of enantiomers has been started in the past and continues to be a topic of
great interest in various fields of research, mainly because these compounds could be …

Recent achievements and future challenges in supercritical fluid chromatography for the enantioselective separation of chiral pharmaceuticals

S Felletti, OH Ismail, C De Luca, V Costa, F Gasparrini… - Chromatographia, 2019 - Springer
During the last years, supercritical fluid chromatography (SFC) has attracted a continuously
growing number of users. Thanks to the introduction of state-of-the-art equipment, this …

Chromatographic supports for enantioselective liquid chromatography: Evolution and innovative trends

C Fernandes, R Lima, MMM Pinto, ME Tiritan - Journal of Chromatography …, 2022 - Elsevier
Diverse approaches have been explored as chromatographic supports for chiral stationary
phases (CSPs) in liquid chromatography (LC), such as the introduction of nanoparticles …