Chemical proteomics, emerging rapidly in recent years, has become a main approach to
identifying interactions between the small molecules and proteins in the cells on a proteome …

Many of the novel ideas that drive today's proteomic technologies are focused essentially on
experimental or data-processing workflows. The latter are implemented and published in a …

Current stage of proteomic research in the field of biology, medicine, development of new
drugs, population screening, or personalized approaches to therapy dictates the need to …

Recently, we presented the DirectMS1 method of ultrafast proteome-wide analysis based on
minute-long LC gradients and MS1-only mass spectra acquisition. Currently, the method …

Proteome-wide analyses rely on tandem mass spectrometry and the extensive separation of
proteolytic mixtures. This imposes considerable instrumental time consumption, which is one …

Proteome characterization relies heavily on tandem mass spectrometry (MS/MS) and is thus
associated with instrumentation complexity, lengthy analysis time, and limited duty cycle. It …

Proteome analysis currently heavily relies on tandem mass spectrometry (MS/MS), which
does not fully utilize MS1 features, as many precursors remain unselected for MS/MS …

Data-independent acquisition (DIA) at the shortened data acquisition time is becoming a
method of choice for quantitative proteomic applications requiring high throughput analysis …

RATIONALE One of the important steps in initial data processing of peptide mass spectra is
the detection of peptide features in full‐range mass spectra. Ion mobility offers advantages …

Protein quantitation in tissue cells or physiological fluids based on liquid
chromatography/mass spectrometry is one of the key sources of information on the …