This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

Studies of neuropeptide and peptide hormone signaling are coming of age in Drosophila
due to rapid developments in molecular genetics approaches that overcome the difficulties …

Cells keep their energy balance and avoid oxidative stress by regulating mitochondrial
movement, distribution, and clearance. We report here that two Parkinson's disease …

The anatomy of many neural circuits is being characterized with increasing resolution, but
their molecular properties remain mostly unknown. Here, we characterize gene expression …

Fast axonal transport (FAT) requires consistent energy over long distances to fuel the
molecular motors that transport vesicles. We demonstrate that glycolysis provides ATP for …

Employing the clear, student-friendly style that made previous editions so popular, Insect
Physiology and Biochemistry, Fourth Edition presents an engaging and authoritative guide …

Adipokinetic hormones (AKHs) are metabolic neuropeptides, mediating mobilization of
energy substrates from the fat body in many insects. In delving into the roles of the …

Cells allocate substantial resources toward monitoring levels of nutrients that can be used
for ATP generation by mitochondria. Among the many specialized cell types, neurons are …

Circadian clocks organize behavior and physiology to adapt to daily environmental cycles.
Genetic approaches in the fruit fly, Drosophila melanogaster, have revealed widely …

Selective genetic manipulation of neuronal function in vivo requires techniques for targeting
gene expression to specific cells. Existing systems accomplish this using the promoters of …