Bioinorganic supramolecular coordination complexes and their biomedical applications
G Moreno‐Alcántar, A Casini - FEBS letters, 2023 - Wiley Online Library
The field of Bioinorganic Supramolecular Chemistry is an emerging research area including
metal‐based supramolecules resulting from coordination‐driven self‐assembly (CDSA) …
metal‐based supramolecules resulting from coordination‐driven self‐assembly (CDSA) …
Functional nucleic acids as modular components against SARS-CoV-2: From diagnosis to therapeutics
W Zhang, N Liu, J Zhang - Biosensors and Bioelectronics, 2022 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19), which poses an extremely serious global
impact on human public healthcare, represents a high transmission and disease-causing …
impact on human public healthcare, represents a high transmission and disease-causing …
Metallodrug Profiling against SARS‐CoV‐2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain‐like Protease PLpro
M Gil‐Moles, S Türck, U Basu… - … A European Journal, 2021 - Wiley Online Library
The global spread of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
has called for an urgent need for dedicated antiviral therapeutics. Metal complexes are …
has called for an urgent need for dedicated antiviral therapeutics. Metal complexes are …
Organometallic pillarplexes that bind DNA 4-way Holliday junctions and forks
JS Craig, L Melidis, HD Williams… - Journal of the …, 2023 - ACS Publications
Holliday 4-way junctions are key to important biological DNA processes (insertion,
recombination, and repair) and are dynamic structures that adopt either open or closed …
recombination, and repair) and are dynamic structures that adopt either open or closed …
[HTML][HTML] Cancer molecular biology and strategies for the design of cytotoxic gold (I) and gold (III) complexes: a tutorial review
D van der Westhuizen, DI Bezuidenhout… - Dalton …, 2021 - pubs.rsc.org
This tutorial review highlights key principles underpinning the design of selected
metallodrugs to target specific biological macromolecules (DNA and proteins). The review …
metallodrugs to target specific biological macromolecules (DNA and proteins). The review …
Internal Dynamics and Modular Peripheral Binding in Stimuli‐Responsive 3: 2 Host: Guest Complexes
Now that the chemistry of 1: 1 host: guest complexes is well‐established, it is surprising to
note that higher stoichiometry (oligomeric) complexes, especially those with excess host …
note that higher stoichiometry (oligomeric) complexes, especially those with excess host …
[HTML][HTML] Natural selection pressure exerted on “Silent” mutations during the evolution of SARS-CoV-2: Evidence from codon usage and RNA structure
From the first emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
till now, multiple mutations that caused synonymous and nonsynonymous substitutions have …
till now, multiple mutations that caused synonymous and nonsynonymous substitutions have …
The Biologically Inspired Abilities of Metallosupramolecular Architectures
AC Pearcy, JD Crowley - Chemistry–A European Journal, 2023 - Wiley Online Library
Natural machinery such as proteins and enzymes can bind substrates and perform intricate
functions on these molecules. This behaviour is mediated by highly ordered but …
functions on these molecules. This behaviour is mediated by highly ordered but …
Small-Molecule 3D Ligand for RNA Recognition: Tuning Selectivity through Scaffold Hopping
S Felder, C Sagné, E Benedetti… - ACS Chemical Biology, 2022 - ACS Publications
Targeting RNAs with small molecules is considered the next frontier for drug discovery. In
this context, the development of compounds capable of binding RNA structural motifs of low …
this context, the development of compounds capable of binding RNA structural motifs of low …
[HTML][HTML] 浅谈广谱抗病毒药物研发的普适性策略
徐淑静, 丁当, 刘新泳, 展鹏 - 药学学报, 2022 - html.rhhz.net
病毒感染疾病严重威胁人类生命健康与社会发展. 为应对未来可能暴发的新发和再现病毒疫情,
研发广谱抗病毒药物成为重要且紧迫的研究课题. 本文精选近年经典案例, 从抗病毒药物研究的 …
研发广谱抗病毒药物成为重要且紧迫的研究课题. 本文精选近年经典案例, 从抗病毒药物研究的 …