As the worldwide population ages, oncologists are often required to make difficult and
complex decisions regarding the treatment of older people (aged 65 years and older) with …

As the mean age of the global population increases, breast cancer in older individuals will
be increasingly encountered in clinical practice. Management decisions should not be …

BACKGROUND: Tools are lacking to assess the individual risk of severe toxicity from
chemotherapy. Such tools would be especially useful for older patients, who vary …

Purpose This is the first randomized phase II/III trial comparing two carboplatin-based
chemotherapy regimens in patients with urothelial cancer who are ineligible (“unfit”) for …

Purpose To provide recommendations for appropriate cytotoxic chemotherapy dosing for
obese adult patients with cancer. Methods The American Society of Clinical Oncology …

Background Platinum-based doublet chemotherapy is recommended to treat advanced non-
small-cell lung cancer (NSCLC) in fit, non-elderly adults, but monotherapy is recommended …

Renal impairment is a common complication of multiple myeloma (MM). The estimated
glomerular filtration rate (eGFR) using the Modification of Diet in Renal Disease formula is …

The current treatment paradigm for muscle-invasive bladder cancer (MIBC) consists of
cisplatin-based neoadjuvant chemotherapy followed by local definitive therapy, or local …

As a result of an increasing life expectancy, the incidence of cancer cases diagnosed in the
older population is rising. Indeed, cancer incidence is 11-fold higher in persons over the age …

Context In addition to classic tumor-related prognostic factors, patient characteristics may be
associated with breast cancer outcome. Objective To assess the association between age at …