iRhom2 regulates ectodomain shedding and surface expression of the major histocompatibility complex (MHC) class I
M Calligaris, DP Spanò, S Bonelli, SA Müller… - Cellular and Molecular …, 2024 - Springer
Proteolytic release of transmembrane proteins from the cell surface, the so called
ectodomain shedding, is a key process in inflammation. Inactive rhomboid 2 (iRhom2) plays …
ectodomain shedding, is a key process in inflammation. Inactive rhomboid 2 (iRhom2) plays …
Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and …
K Bläsius, L Ludwig, S Knapp, C Flaßhove… - Cellular and Molecular …, 2024 - Springer
The protease ADAM17 plays an important role in inflammation and cancer and is regulated
by iRhom2. Mutations in the cytosolic N-terminus of human iRhom2 cause tylosis with …
by iRhom2. Mutations in the cytosolic N-terminus of human iRhom2 cause tylosis with …
[HTML][HTML] FPGA Implementation of Reaction Systems
Z Shang, S Verlan, J Lu, Z Wei, M Zhou - Electronics, 2024 - mdpi.com
Reaction system (RS) belongs to a type of qualitative computing model inspired by
biochemical reactions taking place inside biological cells. It concerns more the interactions …
biochemical reactions taking place inside biological cells. It concerns more the interactions …
Regulation of tmTNF-α Processing by FRMD8 in Triple-Negative Breast Cancer Metastasis: Insights into Molecular Pathway Dynamics
J Xu, X Yang, P Shu, W Wang, H Wu, Z Wang - bioRxiv, 2024 - biorxiv.org
Purpose: Breast cancer remains the leading cause of cancer related mortality among
women worldwide, with late stage diagnoses prevalent in China resulting in significantly …
women worldwide, with late stage diagnoses prevalent in China resulting in significantly …