Modeling antiretroviral drug responses for HIV-1 infected patients using differential equation models

Y Xiao, H Miao, S Tang, H Wu - Advanced drug delivery reviews, 2013 - Elsevier
We review mathematical modeling and related statistical issues of HIV dynamics primarily in
response to antiretroviral drug therapy in this article. We start from a basic model of virus …

Emergence of HIV-1 drug resistance during antiretroviral treatment

L Rong, Z Feng, AS Perelson - Bulletin of mathematical biology, 2007 - Springer
Treating HIV-infected patients with a combination of several antiretroviral drugs usually
contributes to a substantial decline in viral load and an increase in CD4+ T cells. However …

Sparse modeling of human actions from motion imagery

A Castrodad, G Sapiro - International journal of computer vision, 2012 - Springer
An efficient sparse modeling pipeline for the classification of human actions from video is
here developed. Spatio-temporal features that characterize local changes in the image are …

Modelling immune response and drug therapy in human malaria infection

C Chiyaka, W Garira, S Dube - … and Mathematical Methods in …, 2008 - Wiley Online Library
A new intra‐host model of malaria that describes the dynamics of the blood stages of the
parasite and its interaction with red blood cells and immune effectors is proposed. Local and …

Optimal treatment strategies derived from a HIV model with drug-resistant mutants

HD Kwon - Applied Mathematics and Computation, 2007 - Elsevier
This paper presents a mathematical model which is in the form of a system of ordinary
differential equations. These equations describe the dynamics of the immune system …

Dynamical analysis of a multi-strain model of HIV in the presence of anti-retroviral drugs

O Sharomi, AB Gumel - Journal of biological dynamics, 2008 - Taylor & Francis
One major drawback associated with the use of anti-retroviral drugs in curtailing HIV spread
in a population is the emergence and transmission of HIV strains that are resistant to these …

Global dynamics for a drug-sensitive and drug-resistant mixed strains of HIV infection model with saturated incidence and distributed delays

W Chen, Z Teng, L Zhang - Applied Mathematics and Computation, 2021 - Elsevier
In this paper, a drug-sensitive and drug-resistant mixed strains of HIV infection model with
saturated incidence and distributed infection delays is proposed. The drug-sensitive strain …

The global dynamics in a wild-type and drug-resistant HIV infection model with saturated incidence

W Chen, N Tuerxun, Z Teng - Advances in Difference Equations, 2020 - Springer
In this paper we investigate the global dynamics in an HIV virus infection model with
saturated incidence. The model includes two viral strains, one is wild-type (ie drug sensitive) …

Optimal control of an age-structured model of HIV infection

HD Kwon, J Lee, SD Yang - Applied Mathematics and Computation, 2012 - Elsevier
The optimal treatment strategies with an age-structured model of HIV infection are
investigated. The age-structured model allows for variations in the virion production rate and …

Modeling the cytotoxicity of Romidepsin reveals the ineffectiveness of this drug in the “shock and kill” strategy

Q Deng, T Guo, Z Qiu, Y Chen - Chaos, Solitons & Fractals, 2023 - Elsevier
The “shock and kill” strategy is being widely explored to purge Human Immunodeficiency
Virus (HIV) latent reservoirs. Romidepsin, a kind of latency-reversing agents (LRAs), has …