Executive dysfunction is the most important predictor for loss of independence in dementia.
As executive function involves the coordination of distributed cerebral functions, executive …

Neuroimaging biomarkers have potential role in the early diagnosis as well as periodic
follow-up of neurodegenerative diseases such as Alzheimer's disease (AD). Structural …

White matter microstructure can be measured with diffusion tensor imaging (DTI). While
increasing age is a predictor of white matter (WM) microstructure changes, roles of other …

A novel biomarker panel was proposed to quantify macro and microstructural biomarkers
from the normal-appearing brain matter (NABM) in multicentre fluid-attenuation inversion …

Background Ischemic heart disease (IHD) is linked to brain white matter (WM) breakdown
but how age or disease effects WM integrity, and whether it is reversible using cardiac …

Dementia is an evolving challenge in society, and no disease‐modifying treatment exists.
Diagnosis can be demanding and MR imaging may aid as a noninvasive method to …

Physical frailty is an age-related clinical syndrome that is associated with multiple adverse
health outcomes, including cognitive impairment and dementia. Recent studies have shown …

Atherosclerosis can underly internal carotid artery stenosis (ICAS), a major risk factor for
ischemic stroke, as well as small vessel disease (SVD). This study aimed to investigate …

A few studies report that parental longevity is associated with preserved cognition and
physical function and lower risk of Alzheimer's disease. However, data on structural …

Ischemic cerebrovascular diseases relate to a variety of large vessel and small vessel
angiopathies, which are common causes of ischemic stroke and cognitive dysfunction …