Colonization by Pneumocystis jirovecii and its role in disease

A Morris, KA Norris - Clinical microbiology reviews, 2012 - Am Soc Microbiol
Although the incidence of Pneumocystis pneumonia (PCP) has decreased since the
introduction of combination antiretroviral therapy, it remains an important cause of disease in …

Current Understanding of Pneumocystis Immunology

MN Kelly, JE Shellito - Future microbiology, 2010 - Taylor & Francis
Pneumocystis jirovecii is the opportunistic fungal organism that causes Pneumocystis
pneumonia (PCP) in humans. Similar to other opportunistic pathogens, Pneumocystis …

CD4+ T cell–independent vaccination against Pneumocystis carinii in mice

M Zheng, JE Shellito, L Marrero… - The Journal of …, 2001 - Am Soc Clin Investig
Host defenses are profoundly compromised in HIV-infected hosts due to progressive
depletion of CD4+ T lymphocytes. Moreover, deficient CD4+ T lymphocytes impair …

Pneumocystis Pneumonia: Immunity, Vaccines, and Treatments

AD Gingerich, KA Norris, JJ Mousa - Pathogens, 2021 - mdpi.com
For individuals who are immunocompromised, the opportunistic fungal pathogen
Pneumocystis jirovecii is capable of causing life-threatening pneumonia as the causative …

Pneumocystis pneumonia

JJ Lu, CH Lee - Journal of the Formosan Medical Association, 2008 - Elsevier
Pneumocystis pneumonia (PcP) in humans is caused by Pneumocystis jirovecii, which has
recently been reclassified as a fungus because its cell wall composition and nucleotide …

Toll-Like Receptor 2 Mediates Alveolar Macrophage Response to Pneumocystis murina

C Zhang, SH Wang, ME Lasbury, D Tschang… - Infection and …, 2006 - Am Soc Microbiol
The innate immune response to Pneumocystis infection is not well understood. In this study,
normal C57BL/6 mouse alveolar macrophages were found to respond to Pneumocystis …

Vaccine-Induced Immunogenicity and Protection Against Pneumocystis Pneumonia in a Nonhuman Primate Model of HIV and Pneumocystis Coinfection

HM Kling, KA Norris - The Journal of infectious diseases, 2016 - academic.oup.com
Background. The ubiquitous opportunistic pathogen Pneumocystis jirovecii causes
pneumonia in immunocompromised individuals, including human immunodeficiency virus …

Relationship of Pneumocystis jiroveci Humoral Immunity to Prevention of Colonization and Chronic Obstructive Pulmonary Disease in a Primate Model of HIV …

HM Kling, TW Shipley, SP Patil, J Kristoff… - Infection and …, 2010 - Am Soc Microbiol
Pulmonary colonization by the opportunistic pathogen Pneumocystis jiroveci is common in
HIV+ subjects and has been associated with development of chronic obstructive pulmonary …

Transcriptomic Analysis Reveals Significant B Lymphocyte Suppression in Corticosteroid-Treated Hosts with Pneumocystis Pneumonia

Y Hu, D Wang, K Zhai, Z Tong - American Journal of Respiratory …, 2017 - atsjournals.org
Pneumocystis pneumonia (PCP) is an opportunistic, infectious disease that is prevalent in
immunosuppressed hosts. Corticosteroid treatment is the most significant risk factor for …

[HTML][HTML] Immunization with recombinant Pneumocystis carinii p55 antigen provides partial protection against infection: characterization of epitope recognition …

AG Smulian, DW Sullivan, SA Theus - Microbes and infection, 2000 - Elsevier
Many therapeutic options exist for the treatment of Pneumocystis carinii pneumonia, a
common fungal opportunistic pulmonary pathogen, but treatment is often complicated by …