Introduction: Chemokines play a crucial role in breast cancer tumorigenesis and
progression. Recently, the chemokine (CC motif) ligand 5 (CCL5), which can be secreted …

The purpose of this work was to analyze chemokine and chemokine receptor expression in
untreated and in irradiated squamous cell carcinoma of the head and neck (SCCHN) tumor …

Evidence showed that chemokines serve as pro-migratory factors for immune cells. CCL3,
CCL4 and CCL5, as the main CC chemokines subfamily members, activate immune cells …

Abstract Associations between CCL5-403, CCR5-59029, and Delta32 polymorphisms and
cancer risk are inconclusive. To derive a more precise estimation of the association, we …

Objective: To investigate the association of two functional single nucleotide polymorphisms
in the promoter region of the interleukin-18 gene, at positions− 607 and− 137, with head and …

The stromal cell derived factor-1 (SDF-1) rs1801157 gene polymorphism has been
implicated in susceptibility to cancer, but the results were inconclusive. The current study …

Background: Recent evidence has demonstrated the implication of CC chemokine ligand 5
(CCL5) and CC chemokine receptor 5 (CCR5) in breast tumor initiation and progression …

Chemokine CC receptor type 5 (CCR5) is a cell surface receptor that has high affinity for
chemotropic cytokines called chemokines. The CCR5 gene contains a 32 base pairs (bp) …

Background CXCL12 is a small chemotactic cytokine belonging to the CXC chemokine
family expressed in various organs. It contributes to the migration, invasion and …

Abstract Stromal-cell derived factor-1 (SDF-1), a CXC chemokine, is important for growth,
angiogenesis and metastasis of tumor cells. The SDF1-3'A polymorphism has been …