tRNAs as regulators of biological processes
Transfer RNAs (tRNA) are best known for their role as adaptors during translation of the
genetic code. Beyond their canonical role during protein biosynthesis, tRNAs also perform …
genetic code. Beyond their canonical role during protein biosynthesis, tRNAs also perform …
tiRNAs: A novel class of small noncoding RNAs that helps cells respond to stressors and plays roles in cancer progression
Abstract tRNA‐derived stress‐induced RNAs (tiRNAs), important components of tRNA‐
derived fragments, are gaining popularity for their functions as small noncoding RNAs …
derived fragments, are gaining popularity for their functions as small noncoding RNAs …
Small RNAs derived from tRNAs and rRNAs are highly enriched in exosomes from both old and new world Leishmania providing evidence for conserved exosomal …
U Lambertz, ME Oviedo Ovando, EJR Vasconcelos… - BMC genomics, 2015 - Springer
Background Leishmania use exosomes to communicate with their mammalian hosts and
these secreted vesicles appear to contribute to pathogenesis by delivering protein virulence …
these secreted vesicles appear to contribute to pathogenesis by delivering protein virulence …
Uropathogenic Escherichia coli Releases Extracellular Vesicles That Are Associated with RNA
Background Bacterium-to-host signalling during infection is a complex process involving
proteins, lipids and other diffusible signals that manipulate host cell biology for pathogen …
proteins, lipids and other diffusible signals that manipulate host cell biology for pathogen …
Fundamental Roles of the Golgi-Associated Toxoplasma Aspartyl Protease, ASP5, at the Host-Parasite Interface
PM Hammoudi, D Jacot, C Mueller, M Di Cristina… - PLoS …, 2015 - journals.plos.org
Toxoplasma gondii possesses sets of dense granule proteins (GRAs) that either assemble
at, or cross the parasitophorous vacuole membrane (PVM) and exhibit motifs resembling the …
at, or cross the parasitophorous vacuole membrane (PVM) and exhibit motifs resembling the …
Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection
Globally, nearly 2 billion people are infected with the intracellular protozoan Toxoplasma
gondii 1. This persistent infection can cause severe disease in immunocompromised people …
gondii 1. This persistent infection can cause severe disease in immunocompromised people …
mRNA pseudouridylation affects RNA metabolism in the parasite Toxoplasma gondii
MA Nakamoto, AF Lovejoy, AM Cygan, JC Boothroyd - Rna, 2017 - rnajournal.cshlp.org
RNA contains over 100 modified nucleotides that are created post-transcriptionally, among
which pseudouridine (Ψ) is one of the most abundant. Although it was one of the first …
which pseudouridine (Ψ) is one of the most abundant. Although it was one of the first …
Surveillance and cleavage of eukaryotic tRNAs
C Megel, G Morelle, S Lalande, AM Duchêne… - International journal of …, 2015 - mdpi.com
Beyond their central role in protein synthesis, transfer RNAs (tRNAs) have many other
crucial functions. This includes various roles in the regulation of gene expression, stress …
crucial functions. This includes various roles in the regulation of gene expression, stress …
[HTML][HTML] Transfer RNA as a source of small functional RNA
M Shigematsu, S Honda, Y Kirino - Journal of molecular biology …, 2014 - ncbi.nlm.nih.gov
Since their discovery in the 1950s, transfer RNAs (tRNAs) have been best known as adapter
molecules that play a central role in translating genetic information. However, recent …
molecules that play a central role in translating genetic information. However, recent …
[HTML][HTML] Observations on bradyzoite biology
V Tu, R Yakubu, LM Weiss - Microbes and infection, 2018 - Elsevier
Abstract Tachyzoites of the Apicomplexan Toxoplasma gondii cause acute infection,
disseminate widely in their host, and eventually differentiate into a latent encysted form …
disseminate widely in their host, and eventually differentiate into a latent encysted form …