Transcriptional networks orchestrate complex developmental processes. Such networks are
commonly instigated by master regulators of development. Considerable progress has been …

The transcriptional activator AREA is a member of the GATA family of transcription factors
and mediates nitrogen metabolite repression in the fungus Aspergillus nidulans. The …

GATA transcription factors are a group of DNA binding proteins broadly distributed in
eukaryotes. The GATA factors DNA binding domain is a class IV zinc finger motif in the form …

The transcription factor GATA-1 is required for terminal erythroid maturation and functions as
an activator or repressor depending on gene context. Yet its in vivo site selectivity and ability …

The GATA-binding transcription factors comprise a protein family whose members contain
either one or two highly conserved zinc finger DNA-binding domains. Members of this group …

Gene inactivation studies have shown that members of the GATA family of transcription
factors are critical for endoderm differentiation in mice, flies and worms, yet how these …

Background The binding of transcription factors to specific locations in the genome is
integral to the orchestration of transcriptional regulation in cells. To characterize transcription …

Recent studies in transgenic mice have revealed that expression of a dominant negative
form of the transcription factor GATA-3 in T cells can prevent T helper cell type 2 (Th2) …

Androgen receptor (AR) signaling is crucial for driving prostate cancer (PCa), the most
diagnosed and the second leading cause of death in male patients with cancer in the United …

The GATA gene family is one of the most conserved families of transcription factors, playing
a significant role in different aspects of cellular processes, in organisms ranging from fungi to …