[HTML][HTML] The multifaceted PDCD10/CCM3 gene
The programmed cell death 10 (PDCD10) gene was originally identified as an apoptosis-
related gene, although it is now usually known as CCM3, as the third causative gene of …
related gene, although it is now usually known as CCM3, as the third causative gene of …
[HTML][HTML] Non-canonical signaling pathway of SNAI2 induces EMT in ovarian cancer cells by suppressing miR-222-3p transcription and upregulating PDCD10
L Fan, H Lei, S Zhang, Y Peng, C Fu, G Shu, G Yin - Theranostics, 2020 - ncbi.nlm.nih.gov
Background: Epithelial ovarian cancer (EOC) is one of the most lethal malignancies in
women worldwide. Many studies showed the transcription factor SNAI2-induced Epithelial …
women worldwide. Many studies showed the transcription factor SNAI2-induced Epithelial …
Global control regions and regulatory landscapes in vertebrate development and evolution
F Spitz, D Duboule - Advances in genetics, 2008 - Elsevier
During the course of evolution, many genes that control the development of metazoan body
plans were co‐opted to exert novel functions, along with the emergence or modification of …
plans were co‐opted to exert novel functions, along with the emergence or modification of …
miRNA-26a-5p and miR-26b-5p inhibit the proliferation of bladder cancer cells by regulating PDCD10
K Wu, XY Mu, JT Jiang, MY Tan… - Oncology …, 2018 - spandidos-publications.com
MicroRNA (miR)-26a-5p and miR-26b-5p consistently play an antitumor role in many types
of cancers, but the underlying mechanism remains unclear in bladder cancer (BC). In the …
of cancers, but the underlying mechanism remains unclear in bladder cancer (BC). In the …
The gene pair PRR11 and SKA2 shares a NF-Y-regulated bidirectional promoter and contributes to lung cancer development
Y Wang, Y Zhang, C Zhang, H Weng, Y Li, W Cai… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Head-to-head gene pairs represent a unique feature of gene organization in eukaryotes,
accounting for> 10% of genes in the human genome. Identification and functional analysis of …
accounting for> 10% of genes in the human genome. Identification and functional analysis of …
Viral vectors based on bidirectional cell-specific mammalian promoters and transcriptional amplification strategy for use in vitro and in vivo
B Liu, JF Paton, S Kasparov - BMC biotechnology, 2008 - Springer
Background Using cell-type-specific promoters to restrict gene expression to particular cells
is an attractive approach for gene therapy, but often hampered by insufficient transcriptional …
is an attractive approach for gene therapy, but often hampered by insufficient transcriptional …
Anti-Mullerian-hormone-dependent regulation of the brain serine-protease inhibitor neuroserpin
N Lebeurrier, S Launay, R Macrez… - Journal of Cell …, 2008 - journals.biologists.com
The balance between tissue-type plasminogen activator (tPA) and one of its inhibitors,
neuroserpin, has crucial roles in the central nervous system, including the control of …
neuroserpin, has crucial roles in the central nervous system, including the control of …
Gene expression profile of glioblastoma peritumoral tissue: an ex vivo study
A Mangiola, N Saulnier, P De Bonis, D Orteschi… - PLoS …, 2013 - journals.plos.org
The gene expression pattern of glioblastoma (GBM) is well documented but the expression
profile of brain adjacent to tumor is not yet analysed. This may help to understand the …
profile of brain adjacent to tumor is not yet analysed. This may help to understand the …
CCM3/SERPINI1 bidirectional promoter variants in patients with cerebral cavernous malformations: a molecular and functional study
C Scimone, P Bramanti, A Ruggeri, L Donato… - BMC Medical …, 2016 - Springer
Abstract Background Cerebral cavernous malformations (CCMs) are vascular anomalies of
the nervous system mostly located in the brain presenting sporadically or familial. Causes of …
the nervous system mostly located in the brain presenting sporadically or familial. Causes of …
Long non-coding RNA PVT1-mediated miR-543/SERPINI1 axis plays a key role in the regulatory mechanism of ovarian cancer
C Qu, C Dai, Y Guo, R Qin, J Liu - Bioscience Reports, 2020 - portlandpress.com
Purpose: To investigate the regulation mechanism of long non-coding RNA (lncRNA)
plasmocytoma variant translocation 1 (PVT1) in ovarian cancer (OC). Methods: The levels of …
plasmocytoma variant translocation 1 (PVT1) in ovarian cancer (OC). Methods: The levels of …