Liquid biopsies: the future of cancer early detection

S Connal, JM Cameron, A Sala, PM Brennan… - Journal of translational …, 2023 - Springer
Cancer is a worldwide pandemic. The burden it imposes grows steadily on a global scale
causing emotional, physical, and financial strains on individuals, families, and health care …

ESR/ERS statement paper on lung cancer screening

HU Kauczor, AM Baird, TG Blum, L Bonomo… - European …, 2020 - Springer
In Europe, lung cancer ranks third among the most common cancers, remaining the biggest
killer. Since the publication of the first European Society of Radiology and European …

Liquid biopsy in prostate cancer management—Current challenges and future perspectives

F Crocetto, G Russo, E Di Zazzo, P Pisapia, BF Mirto… - Cancers, 2022 - mdpi.com
Simple Summary Prostate cancer (PCa) is a widespread malignancy, representing the
second leading cause of cancer-related death in men. In the last years, liquid biopsy has …

An overview of precision oncology basket and umbrella trials for clinicians

JJH Park, G Hsu, EG Siden… - CA: a cancer journal …, 2020 - Wiley Online Library
With advancements in biomarkers and momentum in precision medicine, biomarker‐guided
trials such as basket trials and umbrella trials have been developed under the master …

Updates on liquid biopsy: Current trends and future perspectives for clinical application in solid tumors

P Pinzani, V D'Argenio, M Del Re… - Clinical Chemistry and …, 2021 - degruyter.com
Despite advances in screening and therapeutics cancer continues to be one of the major
causes of morbidity and mortality worldwide. The molecular profile of tumor is routinely …

Potential utility of liquid biopsy as a diagnostic and prognostic tool for the assessment of solid tumors: implications in the precision oncology

RA Mathai, RVS Vidya, BS Reddy, L Thomas… - Journal of clinical …, 2019 - mdpi.com
Liquid biopsy is a technique that utilizes circulating biomarkers in the body fluids of cancer
patients to provide information regarding the genetic landscape of the cancer. It is emerging …

Evaluating the quantity, quality and size distribution of cell-free DNA by multiplex droplet digital PCR

M Alcaide, M Cheung, J Hillman, SR Rassekh… - Scientific reports, 2020 - nature.com
Cell-free DNA (cfDNA) has become a comprehensive biomarker in the fields of non-invasive
cancer detection and monitoring, organ transplantation, prenatal genetic testing and …

Early diagnosis of ovarian cancer based on methylation profiles in peripheral blood cell-free DNA: a systematic review

SK Terp, MP Stoico, K Dybkær, IS Pedersen - Clinical Epigenetics, 2023 - Springer
Patients diagnosed with epithelial ovarian cancer (OC) have a 5-year survival rate of 49%.
For early-stage disease, the 5-year survival rate is above 90%. However, advanced-stage …

[HTML][HTML] Delivery of polymeric nanostars for molecular imaging and endoradiotherapy through the enhanced permeability and retention (EPR) effect

JACM Goos, A Cho, LM Carter, TR Dilling… - Theranostics, 2020 - ncbi.nlm.nih.gov
Expression levels of biomarkers are generally unknown at initial diagnosis. The
development of theranostic probes that do not rely on biomarker availability would expand …

Resistance to TKIs in EGFR-mutated non-small cell lung cancer: from mechanisms to new therapeutic strategies

A Koulouris, C Tsagkaris, AC Corriero, G Metro… - Cancers, 2022 - mdpi.com
Simple Summary Resistance to tyrosine kinase inhibitors (TKIs) of the epidermal growth
factor receptor (EGFR) in advanced mutant non-small cell lung cancer (NSCLC) constitutes …