Nonalcoholic steatohepatitis: global impact and clinical consequences

K Kabarra, P Golabi, ZM Younossi - Endocrine connections, 2021 - ec.bioscientifica.com
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of liver diseases ranging
from simple fatty infiltration of liver parenchyma to the potentially progressive type of NAFLD …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: an update for 2015–2016

DJ Harvey - Mass Spectrometry Reviews, 2021 - Wiley Online Library
This review is the ninth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

N-glycan MALDI imaging mass spectrometry on formalin-fixed paraffin-embedded tissue enables the delineation of ovarian cancer tissues

AV Everest-Dass, MT Briggs, G Kaur, MK Oehler… - Molecular & Cellular …, 2016 - ASBMB
Ovarian cancer is a fatal gynaecological malignancy in adult women with a five-year overall
survival rate of only 30%. Glycomic and glycoproteomic profiling studies have reported …

Formulation, characterization, and evaluation of the anti-tumor activity of nanosized galangin loaded niosomes on chemically induced hepatocellular carcinoma in rats

S Sabry, T Okda, A Hasan - Journal of Drug Delivery Science and …, 2021 - Elsevier
Galangin (GAL) is a flavonoid with anti-tumor activity. However, its poor solubility results in
low bioavailability thus hindering its clinical application. To overcome this challenge, we …

Glycopattern alteration of glycoproteins in gastrointestinal cancer cell lines and their cell-derived exosomes

J Zhang, Y Qin, Q Jiang, F Li, X Jing… - Journal of Proteome …, 2022 - ACS Publications
Gastrointestinal (GI) cancers constitute the largest portion of all human cancers, and the
most prevalent GI cancers in China are colorectal cancer (CRC), gastric cancer (GC), and …

Altered glycosylation associated with dedifferentiation of hepatocellular carcinoma: a lectin microarray-based study

H Takayama, M Ohta, Y Iwashita, H Uchida, Y Shitomi… - BMC cancer, 2020 - Springer
Background Altered glycosylation associated with hepatocellular carcinoma (HCC) is well
documented. However, few reports have investigated the association between …

Manjari Medika Grape Seed Extract Protects Methotrexate-Induced Hepatic Inflammation: Involvement of NF-κB/NLRP3 and Nrf2/HO-1 Signaling System

K Manna, ZS Khan, M Saha, S Mishra… - Journal of …, 2023 - Taylor & Francis
Objective Grape Seed Extract is a natural source of various polyphenols, which have been
shown to possess potent antioxidant and free radical-scavenging activities. The earlier …

Altered N-linked glycosylation in endometrial cancer

P Mittal, M Briggs, M Klingler-Hoffmann, G Kaur… - Analytical and …, 2021 - Springer
It is well established that cell surface glycans play a vital role in biological processes and
their altered form can lead to carcinogenesis. Mass spectrometry–based techniques have …

Use of mass spectrometry to screen glycan early markers in hepatocellular carcinoma

RM De Oliveira, CA Ornelas Ricart… - Frontiers in …, 2018 - frontiersin.org
Association between altered glycosylation patterns and poor prognosis in cancer points
glycans as potential specific tumor markers. Most proteins are glycosylated and functionally …

MTIF2 impairs 5 fluorouracil-mediated immunogenic cell death in hepatocellular carcinoma in vivo: Molecular mechanisms and therapeutic significance

D Xu, Y Wang, J Wu, Z Zhang, J Chen, M Xie… - Pharmacological …, 2021 - Elsevier
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related morbidity and
mortality; it has been reported that immune cell infiltration is a prognosis factor. Here we …