[HTML][HTML] Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

Protein design: From the aspect of water solubility and stability

R Qing, S Hao, E Smorodina, D Jin, A Zalevsky… - Chemical …, 2022 - ACS Publications
Water solubility and structural stability are key merits for proteins defined by the primary
sequence and 3D-conformation. Their manipulation represents important aspects of the …

[HTML][HTML] Membrane active antimicrobial peptides: translating mechanistic insights to design

J Li, JJ Koh, S Liu, R Lakshminarayanan… - Frontiers in …, 2017 - frontiersin.org
Antimicrobial peptides (AMPs) are promising next generation antibiotics that hold great
potential for combating bacterial resistance. AMPs can be both bacteriostatic and …

Physiological functions of bacterial “multidrug” efflux pumps

PJF Henderson, C Maher, LDH Elbourne… - Chemical …, 2021 - ACS Publications
Bacterial multidrug efflux pumps have come to prominence in human and veterinary
pathogenesis because they help bacteria protect themselves against the antimicrobials …

Constructing ion channels from water-soluble α-helical barrels

AJ Scott, A Niitsu, HT Kratochvil, EJM Lang… - Nature …, 2021 - nature.com
The design of peptides that assemble in membranes to form functional ion channels is
challenging. Specifically, hydrophobic interactions must be designed between the peptides …

[HTML][HTML] The applied anatomy of human skin: A model for regeneration

JM Abdo, NA Sopko, SM Milner - Wound Medicine, 2020 - Elsevier
Autologous keratinocyte cultures and combinations of scaffolds, different cell types, solutions
of macromolecules, or growth factors have contributed to the resurfacing of burns and large …

[HTML][HTML] Antimicrobial susceptibility testing of antimicrobial peptides to better predict efficacy

DK Mercer, MDT Torres, SS Duay, E Lovie… - Frontiers in cellular …, 2020 - frontiersin.org
During the development of antimicrobial peptides (AMP) as potential therapeutics,
antimicrobial susceptibility testing (AST) stands as an essential part of the process in …

[HTML][HTML] Human antimicrobial peptides and proteins

G Wang - Pharmaceuticals, 2014 - mdpi.com
As the key components of innate immunity, human host defense antimicrobial peptides and
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …

[HTML][HTML] Membrane active peptides and their biophysical characterization

FG Avci, B Sariyar Akbulut, E Ozkirimli - Biomolecules, 2018 - mdpi.com
In the last 20 years, an increasing number of studies have been reported on membrane
active peptides. These peptides exert their biological activity by interacting with the cell …

Antimicrobial peptides and copper (II) ions: Novel therapeutic opportunities

J Portelinha, SS Duay, SI Yu, K Heilemann… - Chemical …, 2021 - ACS Publications
The emergence of new pathogens and multidrug resistant bacteria is an important public
health issue that requires the development of novel classes of antibiotics. Antimicrobial …