Abstract The interleukin (IL)-1 family member IL-1α is a ubiquitous and pivotal pro-
inflammatory cytokine. The IL-1α precursor is constitutively present in nearly all cell types in …

Behçet syndrome is a rare, chronic inflammatory disease of unknown aetiopathogenesis,
most commonly presenting with mucocutaneous and ocular manifestations. Vascular …

Alarmins are endogenous, constitutively expressed, chemotacting and immune activating
proteins or peptides released because of non-programmed cell death (ie infections, trauma …

Behçet's syndrome (BS) is a rare systemic vasculitis, characterized by a wide range of
different clinical involvements and unpredictable phases of recurrence and remission. BS …

Behçet's disease (BD) is a chronic, relapsing inflammatory, multisystem disease of unknown
etiology. The disease has a wide clinical spectrum of mucocutaneous lesions and ocular …

Behcet's syndrome (BS) is a chronic systemic inflammatory vasculitis with a wide range of
clinical manifestations including recurrent oral and genital ulcers; cutaneous lesions; and …

Objectives Behçet's disease tends to be more severe in men than women. This study was
undertaken to investigate sex-specific genetic effects in Behçet's disease. Methods A total of …

Behçet syndrome (BS) is a unique type of vasculitis that affects veins and arteries of all
sizes, leading to recurrent vascular events, mostly venous thrombosis. The prevalence of …

Behçet's syndrome (BS) is a systemic vasculitis with several clinical manifestations.
Neutrophil hyperactivation mediates vascular BS pathogenesis, via both a massive reactive …

Objective To evaluate the effectiveness and safety of secukinumab in patients with a
mucosal and articular Behçet's phenotype resistant to conventional and biologic treatment …