Fibrin mechanical properties and their structural origins
RI Litvinov, JW Weisel - Matrix Biology, 2017 - Elsevier
Fibrin is a protein polymer that is essential for hemostasis and thrombosis, wound healing,
and several other biological functions and pathological conditions that involve extracellular …
and several other biological functions and pathological conditions that involve extracellular …
Fibrin matrices as (injectable) biomaterials: formation, clinical use, and molecular engineering
IV Roberts, D Bukhary… - Macromolecular …, 2020 - Wiley Online Library
This review focuses on fibrin, starting from biological mechanisms (its production from
fibrinogen and its enzymatic degradation), through its use as a medical device and as a …
fibrinogen and its enzymatic degradation), through its use as a medical device and as a …
[HTML][HTML] Proteins behaving badly. Substoichiometric molecular control and amplification of the initiation and nature of amyloid fibril formation: lessons from and for …
DB Kell, E Pretorius - Progress in biophysics and molecular biology, 2017 - Elsevier
The chief and largely terminal element of normal blood clotting is considered to involve the
polymerisation of the mainly α-helical fibrinogen to fibrin, with a binding mechanism …
polymerisation of the mainly α-helical fibrinogen to fibrin, with a binding mechanism …
[HTML][HTML] Manipulation of cancer cells in a sessile droplet via travelling surface acoustic waves
The behaviours of microparticles inside a sessile droplet actuated by surface acoustic waves
(SAWs) were investigated, where the SAWs produced an acoustic streaming flow and …
(SAWs) were investigated, where the SAWs produced an acoustic streaming flow and …
Does exercise influence the susceptibility to arterial thrombosis? An integrative perspective
LN Olsen, M Fischer, PA Evans, L Gliemann… - Frontiers in …, 2021 - frontiersin.org
Arterial thrombosis is the primary cause of death worldwide, with the most important risk
factors being smoking, unhealthy diet, and physical inactivity. However, although there are …
factors being smoking, unhealthy diet, and physical inactivity. However, although there are …
Automated fiber diameter and porosity measurements of plasma clots in scanning electron microscopy images
Scanning Electron Microscopy (SEM) is a powerful, high-resolution imaging technique
widely used to analyze the structure of fibrin networks. Currently, structural features, such as …
widely used to analyze the structure of fibrin networks. Currently, structural features, such as …
Gelation under stress: impact of shear flow on the formation and mechanical properties of methylcellulose hydrogels
We demonstrate that small unidirectional applied-stresses during temperature-induced
gelation dramatically change the gel temperature and the resulting mechanical properties …
gelation dramatically change the gel temperature and the resulting mechanical properties …
Engineered molecular therapeutics targeting fibrin and the coagulation system: a biophysical perspective
The coagulation cascade represents a sophisticated and highly choreographed series of
molecular events taking place in the blood with important clinical implications. One key …
molecular events taking place in the blood with important clinical implications. One key …
The effect of hematocrit, fibrinogen concentration and temperature on the kinetics of clot formation of whole blood
U Windberger, C Dibiasi, EM Lotz… - Clinical …, 2020 - content.iospress.com
BACKGROUND: Dynamic mechanical analysis of blood clots can be used to detect the
coagulability of blood. OBJECTIVE: We investigated the kinetics of clot formation by …
coagulability of blood. OBJECTIVE: We investigated the kinetics of clot formation by …
Rheology of fibrous gels under compression
C Sun, PK Purohit - Extreme Mechanics Letters, 2022 - Elsevier
A number of biological tissues and synthetic gels consist of a fibrous network infused with
liquid. There have been a few experimental studies of the rheological properties of such gels …
liquid. There have been a few experimental studies of the rheological properties of such gels …