Several hypertension guidelines have removed beta-blockers from their previous position as
first-choice drugs for the treatment of hypertension. However, this downgrading may not be …

Vertebrates developed pulmonary circulation and septated the heart into venous and arterial
compartments, as the adaptation from aquatic to terrestrial life requires more oxygen and …

Cardiac anatomy plays a crucial role in determining cardiac function. However, there is a
poor understanding of how specific and localised anatomical changes affect different …

A index of non-invasive myocardial work (MWI) can account for pressure during the
assessment of cardiac function, potentially separating the influence of loading conditions …

Background Echocardiography provides complex data on cardiac function that can be
integrated into patterns of dysfunction related to the severity of cardiac disease. The aim of …

Abstract Aims Hypertensive patients of African-ancestry (Afr-a) have higher incidences of
heart failure and worse clinical outcomes than hypertensive patients of European-ancestry …

Background: Basal septal hypertrophy (BSH) is an asymmetric, localized thickening of the
upper interventricular septum and constitutes a marker of an early remodelling in patients …

Hypertension mediated organ damage (HMOD) refers to structural or functional changes in
arteries or target organs that can be present in long-standing hypertension, but it can be also …

Background The sigmoid septum has been generally evaluated subjectively and
qualitatively, without detailed examination of its diversity, impact on the morphology of the …

Background We investigated whether ethnicity and sex are associated with different clinical
presentations and cardiovascular magnetic resonance (CMR) findings in individuals with …