Epigenetics, fragmentomics, and topology of cell-free DNA in liquid biopsies
BACKGROUND Liquid biopsies that are based on analysis of cell-free DNA from plasma
offer diagnostic information that is otherwise accessible conventionally through invasive …
offer diagnostic information that is otherwise accessible conventionally through invasive …
DNA sequencing at 40: past, present and future
This review commemorates the 40th anniversary of DNA sequencing, a period in which we
have already witnessed multiple technological revolutions and a growth in scale from a few …
have already witnessed multiple technological revolutions and a growth in scale from a few …
Cell-free DNA comprises an in vivo nucleosome footprint that informs its tissues-of-origin
Nucleosome positioning varies between cell types. By deep sequencing cell-free DNA
(cfDNA), isolated from circulating blood plasma, we generated maps of genome-wide in vivo …
(cfDNA), isolated from circulating blood plasma, we generated maps of genome-wide in vivo …
Liquid biopsy in breast cancer: A comprehensive review
S Alimirzaie, M Bagherzadeh, MR Akbari - Clinical genetics, 2019 - Wiley Online Library
Breast cancer is the most common cancer among women worldwide. Due to its complexity in
nature, effective breast cancer treatment can encounter many challenges. Traditional …
nature, effective breast cancer treatment can encounter many challenges. Traditional …
Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments
Plasma consists of DNA released from multiple tissues within the body. Using genome-wide
bisulfite sequencing of plasma DNA and deconvolution of the sequencing data with …
bisulfite sequencing of plasma DNA and deconvolution of the sequencing data with …
Sequencing of circulating cell-free DNA during pregnancy
DW Bianchi, RWK Chiu - New England Journal of Medicine, 2018 - Mass Medical Soc
Sequencing of Circulating Cell-free DNA during Pregnancy | New England Journal of Medicine
Skip to main content The New England Journal of Medicine homepage Advanced Search …
Skip to main content The New England Journal of Medicine homepage Advanced Search …
What is next generation sequencing?
S Behjati, PS Tarpey - Archives of Disease in Childhood-Education and …, 2013 - ep.bmj.com
Next generation sequencing (NGS), massively parallel or deep sequencing are related
terms that describe a DNA sequencing technology which has revolutionised genomic …
terms that describe a DNA sequencing technology which has revolutionised genomic …
Analysis of cell‐free DNA in maternal blood in screening for fetal aneuploidies: updated meta‐analysis
MM Gil, MS Quezada, R Revello… - … in obstetrics & …, 2015 - Wiley Online Library
Objective To review clinical validation or implementation studies of maternal blood cell‐free
(cf) DNA analysis and define the performance of screening for fetal trisomies 21, 18 and 13 …
(cf) DNA analysis and define the performance of screening for fetal trisomies 21, 18 and 13 …
Molecular roles and function of circular RNAs in eukaryotic cells
LM Holdt, A Kohlmaier, D Teupser - Cellular and Molecular Life Sciences, 2018 - Springer
Protein-coding and noncoding genes in eukaryotes are typically expressed as linear
messenger RNAs, with exons arranged colinearly to their genomic order. Recent advances …
messenger RNAs, with exons arranged colinearly to their genomic order. Recent advances …
Blood-based analyses of cancer: circulating tumor cells and circulating tumor DNA
DA Haber, VE Velculescu - Cancer discovery, 2014 - AACR
The ability to study nonhematologic cancers through noninvasive sampling of blood is one
of the most exciting and rapidly advancing fields in cancer diagnostics. This has been driven …
of the most exciting and rapidly advancing fields in cancer diagnostics. This has been driven …