Simple Summary Epigenetic mechanisms including methylation play an essential role in
regulating gene expression not only in cancer cells but also in immune cells. Although role …

Dendritic cells (DCs) are major regulators of adaptive immunity, as they are not only capable
to induce efficient immune responses, but are also crucial to maintain peripheral tolerance …

Metastatic dissemination of epithelial ovarian cancer (EOC) predominantly occurs through
direct cell shedding from the primary tumor into the intra-abdominal cavity that is filled with …

Graft-vs.-host disease (GVHD) remains a significant cause of morbidity and mortality after
allogeneic hematopoietic stem cell transplantation (allo-HSCT). Significant progresses have …

Dendritic cells (DCs) play a critical immuno-modulating role in pregnancy, which requires
the maternal immune system to tolerate semiallogeneic fetus and at the same time to …

Dendritic cells (DC) are a diverse group of leukocytes responsible for bridging innate and
adaptive immunity. Despite their functional versatility, DCs exist primarily in two basic …

Asthma is a complex trait, often associated with atopy. The genetic contribution has been
evidenced by familial occurrence. Genome-wide association studies allowed for associating …

Plasmacytoid dendritic cells (pDCs) promote viral elimination by producing large amounts of
Type I interferon. Recent studies have shown that pDCs regulate the pathogenesis of …

Immune dysfunction in the tumor microenvironment occurs through epigenetic changes in
both tumor cells and immune cells that alter transcriptional programs driving cell fate and …

Dendritic cell (DC) progenitors adapt their transcriptional program during development,
generating different subsets. How chromatin modifications modulate these processes is …