[HTML][HTML] Pulmonary innate immune response determines the outcome of inflammation during pneumonia and sepsis-associated acute lung injury
V Kumar - Frontiers in immunology, 2020 - frontiersin.org
The lung is a primary organ for gas exchange in mammals that represents the largest
epithelial surface in direct contact with the external environment. It also serves as a crucial …
epithelial surface in direct contact with the external environment. It also serves as a crucial …
[HTML][HTML] Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression
G Schönrich, MJ Raftery, Y Samstag - Advances in biological regulation, 2020 - Elsevier
Abstract Pandemic coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …
Quercetin prevents LPS-induced oxidative stress and inflammation by modulating NOX2/ROS/NF-kB in lung epithelial cells
OJ Sul, SW Ra - Molecules, 2021 - mdpi.com
Oxidative stress caused by the production of reactive oxygen species (ROS) plays a major
role in inflammatory processes. We hypothesized that modulation of ROS via quercetin may …
role in inflammatory processes. We hypothesized that modulation of ROS via quercetin may …
Fe-curcumin nanozyme-mediated reactive oxygen species scavenging and anti-inflammation for acute lung injury
R Yuan, Y Li, S Han, X Chen, J Chen, J He… - ACS central …, 2021 - ACS Publications
Pneumonia, such as acute lung injury (ALI), has been a type of lethal disease that is
generally caused by uncontrolled inflammatory response and excessive generation of …
generally caused by uncontrolled inflammatory response and excessive generation of …
Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms
YQ He, CC Zhou, LY Yu, L Wang, JL Deng… - Pharmacological …, 2021 - Elsevier
Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome
(ARDS) as common life-threatening lung diseases with high mortality rates are mostly …
(ARDS) as common life-threatening lung diseases with high mortality rates are mostly …
[HTML][HTML] Pulmonary delivery of siRNA against acute lung injury/acute respiratory distress syndrome
M Zoulikha, Q Xiao, GF Boafo, MA Sallam… - … Pharmaceutica Sinica B, 2022 - Elsevier
The use of small interfering RNAs (siRNAs) has been under investigation for the treatment of
several unmet medical needs, including acute lung injury/acute respiratory distress …
several unmet medical needs, including acute lung injury/acute respiratory distress …
[HTML][HTML] Understanding the role of neutrophils in acute respiratory distress syndrome
Acute respiratory distress syndrome (ARDS) is difficult to treat and is associated with a high
mortality rate. The most severe form of coronavirus disease 2019 (COVID-19) also leads to …
mortality rate. The most severe form of coronavirus disease 2019 (COVID-19) also leads to …
Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages
Y Guo, Y Liu, S Zhao, W Xu, Y Li, P Zhao… - Nature …, 2021 - nature.com
Oxidative stress contributes to the pathogenesis of acute lung injury. Protein S-
glutathionylation plays an important role in cellular antioxidant defense. Here we report that …
glutathionylation plays an important role in cellular antioxidant defense. Here we report that …
Oxidative stress and respiratory diseases in preterm newborns
L Cannavò, S Perrone, V Viola, L Marseglia… - International journal of …, 2021 - mdpi.com
Premature infants are exposed to increased generation of reactive oxygen species, and on
the other hand, they have a deficient antioxidant defense system. Oxidative insult is a salient …
the other hand, they have a deficient antioxidant defense system. Oxidative insult is a salient …
NADPH oxidase family proteins: signaling dynamics to disease management
Reactive oxygen species (ROS) are pervasive signaling molecules in biological systems. In
humans, a lack of ROS causes chronic and extreme bacterial infections, while uncontrolled …
humans, a lack of ROS causes chronic and extreme bacterial infections, while uncontrolled …