Organoids—cellular aggregates derived from stem or progenitor cells that recapitulate organ
function in miniature—are of growing interest in developmental biology and medicine …

Microfluidics has recently emerged as a powerful tool in generation of submillimeter-sized
cell aggregates capable of performing tissue-specific functions, so-called microtissues, for …

Epithelial organoids are most efficiently grown from mouse-tumour-derived, reconstituted
extracellular matrix hydrogels, whose poorly defined composition, batch-to-batch variability …

Polymer-based hydrogels are hydrophilic polymer networks with crosslinks widely applied
for drug delivery applications because of their ability to hold large amounts of water and …

Tissue and organ biology are very challenging to study in mammals, and progress can be
hindered, particularly in humans, by sample accessibility and ethical concerns. However …

Biomedical hydrogels as sole repair matrices or combined with pre-seeded cells and
bioactive growth factors are extensively applied in tissue engineering and regenerative …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Hydrogels are highly water-swollen molecular networks that are ideal platforms to create
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …

Over the past decades, significant progress has been made in the field of hydrogels as
functional biomaterials. Biomedical application of hydrogels was initially hindered by the …

The key attribute of the thiol-Michael addition reaction that makes it a prized tool in materials
science is its modular “click” nature, which allows for the implementation of this highly …