The retrotrapezoid nucleus: central chemoreceptor and regulator of breathing automaticity

PG Guyenet, RL Stornetta, GMPR Souza… - Trends in …, 2019 - cell.com
The ventral surface of the rostral medulla oblongata has been suspected since the 1960s to
harbor central respiratory chemoreceptors [ie, acid-activated neurons that regulate breathing …

[HTML][HTML] Sex differences in breathing

LH Gargaglioni, DA Marques, LGA Patrone - … Biochemistry and Physiology …, 2019 - Elsevier
Breathing is a vital behavior that ensures both the adequate supply of oxygen and the
elimination of CO 2, and it is influenced by many factors. Despite that most of the studies in …

Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis

S Schuchmann, D Schmitz, C Rivera, S Vanhatalo… - Nature medicine, 2006 - nature.com
Febrile seizures are frequent during early childhood, and prolonged (complex) febrile
seizures are associated with an increased susceptibility to temporal lobe epilepsy. The …

Connexin hemichannel‐mediated CO2‐dependent release of ATP in the medulla oblongata contributes to central respiratory chemosensitivity

RTR Huckstepp, R Id Bihi, R Eason… - The Journal of …, 2010 - Wiley Online Library
Arterial, a major determinant of breathing, is detected by chemosensors located in the
brainstem. These are important for maintaining physiological levels of in the blood and …

Role of parafacial nuclei in control of breathing in adult rats

RTR Huckstepp, KP Cardoza… - Journal of …, 2015 - Soc Neuroscience
Contiguous brain regions associated with a given behavior are increasingly being divided
into subregions associated with distinct aspects of that behavior. Using recently developed …

Medullary serotonin neurons and central CO2 chemoreception

AE Corcoran, MR Hodges, Y Wu, W Wang… - Respiratory physiology …, 2009 - Elsevier
Serotonergic (5-HT) neurons are putative central respiratory chemoreceptors, aiding in the
brain's ability to detect arterial changes in [Formula: see text] and implement appropriate …

The locus coeruleus and central chemosensitivity

LH Gargaglioni, LK Hartzler, RW Putnam - Respiratory physiology & …, 2010 - Elsevier
The locus coeruleus (LC) lies in the dorsal pons and supplies noradrenergic (NA) input to
many regions of the brain, including respiratory control areas. The LC may provide tonic …

The role of maternal smoking in sudden fetal and infant death pathogenesis

N Bednarczuk, A Milner, A Greenough - Frontiers in neurology, 2020 - frontiersin.org
Maternal smoking is a risk factor for both sudden infant death syndrome (SIDS) and sudden
intrauterine unexplained death syndrome (SIUDS). Both SIDS and SIUDS are more …

The role of CO2 and central chemoreception in the control of breathing in the fetus and the neonate

RA Darnall - Respiratory physiology & neurobiology, 2010 - Elsevier
Central chemoreception is active early in development and likely drives fetal breathing
movements, which are influenced by a combination of behavioral state and powerful …

[HTML][HTML] The potential of methylxanthine-based therapies in pediatric respiratory tract diseases

A Oñatibia-Astibia, E Martínez-Pinilla, R Franco - Respiratory medicine, 2016 - Elsevier
Caffeine, theophylline and theobromine are the most known methylxanthines as they are
present in coffee, tea and/or chocolate. In the last decades, a huge experimental effort has …