A guide to the composition and functions of the extracellular matrix

NK Karamanos, AD Theocharis, Z Piperigkou… - The FEBS …, 2021 - Wiley Online Library
Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …

Bioactive potential of natural biomaterials: Identification, retention and assessment of biological properties

K Joyce, GT Fabra, Y Bozkurt, A Pandit - Signal transduction and …, 2021 - nature.com
Biomaterials have had an increasingly important role in recent decades, in biomedical
device design and the development of tissue engineering solutions for cell delivery, drug …

Glycosaminoglycan–protein interactions: the first draft of the glycosaminoglycan interactome

SD Vallet, O Clerc… - Journal of Histochemistry …, 2021 - journals.sagepub.com
The six mammalian glycosaminoglycans (GAGs), chondroitin sulfate, dermatan sulfate,
heparin, heparan sulfate, hyaluronan, and keratan sulfate, are linear polysaccharides …

Ten years of extracellular matrix proteomics: accomplishments, challenges, and future perspectives

A Naba - Molecular & Cellular Proteomics, 2023 - ASBMB
The extracellular matrix (ECM) is a complex assembly of hundreds of proteins forming the
architectural scaffold of multicellular organisms. In addition to its structural role, the ECM …

The role of extracellular matrix in skin wound healing

NN Potekaev, OB Borzykh, GV Medvedev… - Journal of Clinical …, 2021 - mdpi.com
Impaired wound healing is one of the unsolved problems of modern medicine, affecting
patients' quality of life and causing serious economic losses. Impaired wound healing can …

[HTML][HTML] The liver matrisome–looking beyond collagens

GE Arteel, A Naba - Jhep Reports, 2020 - Elsevier
The extracellular matrix (ECM) is a diverse microenvironment that maintains bidirectional
communication with surrounding cells to regulate cell and tissue homeostasis. The classical …

Biomarkers in neurodegenerative diseases: proteomics spotlight on ALS and Parkinson's disease

R Raghunathan, K Turajane, LC Wong - International Journal of …, 2022 - mdpi.com
Neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson's
disease (PD) are both characterized by pathogenic protein aggregates that correlate with …

In-depth matrisome and glycoproteomic analysis of human brain glioblastoma versus control tissue

MK Sethi, M Downs, C Shao, WE Hackett… - Molecular & Cellular …, 2022 - ASBMB
Glioblastoma (GBM) is the most common and malignant primary brain tumor. The
extracellular matrix, also known as the matrisome, helps determine glioma invasion …

[HTML][HTML] Osteoblast/fibroblast coculture derived bioactive ECM with unique matrisome profile facilitates bone regeneration

M Li, A Zhang, J Li, J Zhou, Y Zheng, C Zhang, D Xia… - Bioactive Materials, 2020 - Elsevier
Extracellular matrix (ECM) with mimetic tissue niches was attractive to facilitate tissue
regeneration in situ via recruitment of endogenous cells and stimulation of self-healing …

Matrisome changes in Parkinson's disease

M Downs, MK Sethi, R Raghunathan, MD Layne… - Analytical and …, 2022 - Springer
Extracellular matrix (ECM) proteins, collectively known as the matrisome, include collagens,
glycoproteins, and proteoglycans. Alterations in the matrisome have been implicated in the …