Myocarditis is a complex disease because multiple pathogenetic mechanisms play a role.
While these mechanisms appear to act in a chronological cascade, they undoubtedly …

Angiotensin-converting enzyme (ACE) is a zinc-dependent dipeptidyl carboxypeptidase and
is crucial in the renin-angiotensin-aldosterone system (RAAS) but also implicated in immune …

In 200581, the endemic area at risk for vectorial transmission of CD in Latin America
comprised 19 countries, and involved 108,595,000 people. In 1950, actions against the …

Em 200581, a área endêmica com risco de transmissão vetorial da DC na América Latina
englobava 19 países, com 108.595. 000 pessoas expostas ao risco. Em 1950, iniciaramse …

Up to 18 million of individuals are infected by the protozoan parasite Trypanosoma cruzi in
Latin America, one third of whom will develop chronic Chagas disease cardiomyopathy …

OBJECTIVE: The objective of this study was to determine the safety and efficacy of renin-
angiotensin system (RAS) inhibitors and β-blockers in chronic Chagas cardiomyopathy …

Berberine, an alkaloid derivative extracted from numerous plants of the general Berberis
and Coptis, has been reported to have immunomodulatory effects against immune-mediated …

Trypanosoma cruzi, the aetiological agent of Chagas disease, invades nucleated
mammalian cells including macrophages. In this study, we investigated the crosstalk …

Captopril, an angiotensin-converting enzyme inhibitor, is widely used in the treatment of a
variety of cardiomyopathies, but its effect on autoimmune myocarditis has not been …

Objective The renin–angiotensin system plays an important role in the regulation of
cardiovascular, renal, and endocrine functions. Recent studies have demonstrated that …