The neural crest is a stem/progenitor cell population that contributes to a wide variety of
derivatives, including sensory and autonomic ganglia, cartilage and bone of the face and …

The development of the vertebrate eyes is a complex process starting from anterior-posterior
and dorso-ventral patterning of the anterior neural tube, resulting in the formation of the eye …

Ocular lens development represents an advantageous system in which to study regulatory
mechanisms governing cell fate decisions, extracellular signaling, cell and tissue …

Cranial placodes (which include the adenohypophyseal, olfactory, lens, otic, lateral line,
profundal/trigeminal, and epibranchial placodes) give rise to many sense organs and …

The neural crest and craniofacial placodes are two distinct progenitor populations that arise
at the border of the vertebrate neural plate. This border region develops through a series of …

Specialized sensory organs in the vertebrate head originate from thickenings in the
embryonic ectoderm called cranial sensory placodes. These placodes, as well as the neural …

In the vertebrate head, crucial parts of the sense organs and sensory ganglia develop from
special regions, the cranial placodes. Despite their cellular and functional diversity, they …

Abstract The Eyes Absent (EYA) proteins, first described in the context of fly eye
development, are now implicated in processes as disparate as organ development, innate …

In mammals, the permanence of many forms of hearing loss is the result of the inner ear's
inability to replace lost sensory hair cells. Here, we apply a differentiation strategy to guide …

Cranial sensory placodes derive from discrete patches of the head ectoderm and give rise to
numerous sensory structures. During gastrulation, a specialized “neural border zone” forms …