Browning of the white adipose tissue regulation: New insights into nutritional and metabolic relevance in health and diseases

SA Machado, G Pasquarelli-do-Nascimento… - Nutrition & …, 2022 - Springer
Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining
health and homeostasis. Although white adipose tissue and brown adipose tissue are …

Brown adipose tissue development and metabolism

SM Jung, J Sanchez-Gurmaches, DA Guertin - Brown adipose tissue, 2019 - Springer
Brown adipose tissue is well known to be a thermoregulatory organ particularly important in
small rodents and human infants, but it was only recently that its existence and significance …

Brown adipose tissue heterogeneity, energy metabolism, and beyond

AB Shinde, A Song, QA Wang - Frontiers in endocrinology, 2021 - frontiersin.org
Brown adipocyte in brown adipose tissue (BAT) specializes in expending energy through
non-shivering thermogenesis, a process that produces heat either by uncoupling protein 1 …

Beyond energy balance regulation: The underestimated role of adipose tissues in host defense against pathogens

J Barthelemy, G Bogard, I Wolowczuk - Frontiers in Immunology, 2023 - frontiersin.org
Although the adipose tissue (AT) is a central metabolic organ in the regulation of whole-
body energy homeostasis, it is also an important endocrine and immunological organ. As an …

Adipose tissue, immune aging, and cellular senescence

D Frasca, BB Blomberg - Seminars in immunopathology, 2020 - Springer
Obesity represents a serious health problem as it is rapidly increasing worldwide. Obesity is
associated with reduced healthspan and lifespan, decreased responses to infections and …

Brown and brite: the fat soldiers in the anti-obesity fight

S Srivastava, RL Veech - Frontiers in physiology, 2019 - frontiersin.org
Brown adipose tissue (BAT) is proposed to maintain thermal homeostasis through
dissipation of chemical energy as heat by the uncoupling proteins (UCPs) present in their …

Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice

A Park, K Kim, I Park, SH Lee, KY Park, M Jung… - Nature …, 2023 - nature.com
Brown adipose tissue (BAT) has abundant mitochondria with the unique capability of
generating heat via uncoupled respiration. Mitochondrial uncoupling protein 1 (UCP1) is …

ComBATing aging—does increased brown adipose tissue activity confer longevity?

J Darcy, YH Tseng - Geroscience, 2019 - Springer
Brown and its related beige adipose tissue (BAT) play a definitive role in maintaining body
temperature by producing heat through uncoupling protein 1 (UCP1), which acts by …

The use of infrared thermography in the measurement and characterization of brown adipose tissue activation

J Law, J Chalmers, DE Morris, L Robinson, H Budge… - Temperature, 2018 - Taylor & Francis
Interest in brown adipose tissue has increased in recent years as a potential target for novel
obesity, diabetes and metabolic disease treatments. One of the significant limitations to rapid …

[HTML][HTML] Recent advances in our understanding of brown and beige adipose tissue: the good fat that keeps you healthy

ME Symonds, P Aldiss, M Pope, H Budge - F1000Research, 2018 - ncbi.nlm.nih.gov
Brown adipose tissue (BAT) possesses a unique uncoupling protein (UCP1) which, when
activated, enables the rapid generation of heat and the oxidation of lipids or glucose or both …