Inositol 1, 4, 5-trisphosphate receptors (IP3Rs), by releasing Ca2+ from the endoplasmic
reticulum (ER) of animal cells, allow Ca2+ to be redistributed from the ER to the cytosol or …

Fertilization calcium waves are introduced, and the evidence from which we can infer
general mechanisms of these waves is presented. The two main classes of hypotheses put …

Animals rely on the relative timing of events in their environment to form and update
predictive associations, but the molecular and circuit mechanisms for this temporal …

Inositol 1, 4, 5-trisphosphate receptors (IP3R) and their relatives, ryanodine receptors, are
the channels that most often mediate Ca2+ release from intracellular stores. Their regulation …

A rise in cytosolic Ca 2+ concentration is used as a universal signalling mechanism to
control biological processes as diverse as exocytosis, contraction, cell growth and cell …

Ca2+ is one of the most important messengers. It transmits signals inside living cells and
takes part in intercellular coordination. The dynamics of the Ca2+ concentration shows a …

A pivotal component of the calcium (Ca2+) signaling toolbox in cells is the inositol 1, 4, 5-
triphosphate (IP3) receptor (IP3R), which mediates Ca2+ release from the endoplasmic …

Inositol 1, 4, 5-trisphosphate (IP3) receptors are the intracellular Ca2+ channels most
commonly involved in allowing receptors in the plasma membrane to stimulate release of …

Inositol 1, 4, 5-trisphosphate (IP3) receptors are tetrameric intracellular Ca2+ channels, the
opening of which is regulated by both IP3 and Ca2+. We suggest that all IP3 receptors are …

Ca 2+ oscillations have been considered to obey deterministic dynamics for almost two
decades. We show for four cell types that Ca 2+ oscillations are instead a sequence of …