Background Probiotics play a vital role in treating immune and inflammatory diseases by
improving intestinal barrier function; however, a comprehensive evaluation is missing. The …

Background Critical illness is characterized by a loss of commensal flora and an overgrowth
of potentially pathogenic bacteria, leading to a high susceptibility to nosocomial infections …

Abstract Coronavirus disease 2019 (COVID-19) is a highly contagious infectious disease.
Similar to H7N9 infection, pneumonia and cytokine storm are typical clinical manifestations …

Background. Alzheimer's disease (AD) is the most common cause of dementia in elderly
patients. Recently, several studies have shown that inflammation and oxidative stress …

A growing body of evidence now highlights a key role for inflammation in mediating sickness
behaviors and depression. Systemic inflammatory diseases such as rheumatoid arthritis …

OBJECTIVES: To determine the safety and efficacy of probiotics or synbiotics on morbidity
and mortality in critically ill adults and children. DATA SOURCES: We searched MEDLINE …

Background & aims Several systematic reviews and meta-analyses of randomized
controlled trials concluded that probiotics administration in critically ill patients was safe and …

The pandemic of Coronavirus disease 2019 (COVID-19) is rapidly progressing, causing
significant morbidity and mortality. Various antiviral drugs, anti-inflammatory drugs and …

Gut microflora contribute greatly to immune and nutritive functions and act as a physical
barrier against pathogenic organisms across the gut mucosa. Critical illness disrupts the …

Objectives: To evaluate the effect of probiotics on cytokines in children with severe sepsis.
Design: Randomized, double-blind, placebo-controlled trial. Setting: ICU of a tertiary care …